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What are you doing at ISAS, Konrad?

Dortmund, 21st November 2022

Bei seinem Besuch im Labor erhält Konrad (links) einen Einblick in die Arbeit der Forschungsgruppe Bioimaging.
© ISAS

Visiting the lab, Konrad (left) gets an insight into the work of the Bioimaging research group.

Konrad Krug is a mathematician and he never wanted to work for an insurance company. Since September 2022, he has been a trainee in the Communications unit at the Leibniz Association’s office. Konrad’s main field of work is the magazine ‘leibniz’. The 32-year-old writes articles, prepares contributions for social media and researches pictures. He also contributes to other internal and external communication activities.

  • I am at ISAS because…

    I was just in the area anyway :-). Just kidding, I‘m always happy to have the opportunity to broaden my knowledge. Besides, I want to see as many Leibnizians in action as possible during my traineeship, so that I can experience the world of science from more than just my desk.

  • In the lab…

    I learned, above all, to appreciate the world of the very, very tiny again! It’s great to see the complexity that microscopes can bring to light – and how kind and welcoming the researchers are who operate them.

  • I would have never thought that…

    I would wear a lab coat again in my life – the last time was probably in biology or chemistry class in high school. And that must have been about 15 years ago.

  • About my visit…

    I‘m going to tell everyone I can – especially my grandma, who I‘m going to see tomorrow!

In times of pandemic, species extinction & climate crisis, communication between science & the public is more important than ever for Konrad. Why is he so enthusiastic about science communication? If you have a thirst for knowledge that is hard to quench, Konrad says, you will always find what you are looking for in science communication.

At ISAS, things continued outside the lab for Konrad after his visit to the Bioimaging research group. At AMBIOM – Analysis of Microscopic BIOMedical Images, the 32-year-old explored the challenges of analysing microscope images, & learned how Artificial intelligence can significantly improve the analysis of tumour cells.

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Further articles

Four perspectives on a shared discovery

Although CD177⁺ and CD177⁻ neutrophils look identical under the microscope, they are in fact not the same. Four of the authors of “CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumour-Promoting Activity” (Advanced Science) explain how they identified the functional differences between these immune cells and which combined analytical methods made their discovery possible in the first place. This insight into their research demonstrates how interdisciplinary collaboration can reveal previously undiscovered information.

Das Foto zeigt eine Collage mit Porträts von vier Personen und Mikroskopaufnahmen der Immunzellen Neutrophilen Granulozyten; Von oben links nach rechts: Prof. Dr. Matthias Gunzer, Prof. Dr. Jianxu Chen, Dr. Belal Alshaar und Prof. Dr. Albert Sickmann.

3 Questions for Neele Rottmann

In the lab, Neele Rottmann prepares human and animal samples for mass spectrometry analysis. As part of the HI-FIVE project, she is helping to identify changes at the protein level in heart failure. Why does she spend so much time in the lab working on separations? The technical assistant shares the answer in this interview.

Neele Rottmann is wearing a white lab coat and purple gloves and is operating a mass spectrometry analyser in a laboratory. Next to her is a liquid chromatography system connected to a mass spectrometer via several tubes. There are numerous sample vials on the instrument. As she places a sample into the system, she looks into the camera.

High-tech against Cardiovascular Diseases: 3D Images of Blood Vessels

How do atherosclerotic plaques form in the coronary arteries? At ISAS, researchers are investigating cellular changes in human coronary arteries using techniques such as 3D imaging. During her internship, early-career researcher Leonie Menzel used a light sheet fluorescence microscope to analyse the spatial distribution of individual cells within the tissue. She thereby gained valuable methodological experience for her Master’s thesis.

3 Questions for Lukas Fu

How can AI support the analysis of biomedical images? This was the question Lukas Fu explored during his school internship at ISAS. The 15-year-old also successfully completed his first programming project.

Lukas Fu, a 15-year-old with short black hair. He is wearing glasses and is sitting on a low wall.

Separating Fluorescence Signals Faster and More Precisely with AI

When different fluorescence signals overlap during microscopy, their clear assignment to specific biological structures becomes difficult. To address this common problem, Dr Davide Panzeri is developing AI-based signal separation methods. The biophysicist has been awarded a Marie Skłodowska-Curie Fellowship by the European Union for his promising research project.

Porträt Dr. Davide Panzeri.

Passionate Research, Shaping the Future

How do GRK5 inhibitors work at the cellular level and within the living organism? Biologist Dr Susanne Grund is working with her colleagues at HI-FIVE on a new therapeutic approach for heart failure. In this portrait, she describes what her day-to-day work looks like, balancing research on human stem cells with studies on mice.

ISAS BFF Uploader

What are you doing at ISAS, Theresa?

Why do mice undergo ultrasound examinations of their hearts? What does a typical working day in the lab involve for a technical assistant in the HI-FIVE research project ? And what challenges does the job present? Theresa Pietz provides fascinating insights into her duties, motivations and experiences working with animals.

Study with Heart: A Doctor Bridging Clinic & Laboratory

What is actually happening behind the scenes of a patient trial? Anna Ruzhyna is a clinical research associate who looks after participants with heart failure as part of the HI-FIVE project. She explains how her work helps to develop new therapeutic approaches for the treatment of heart failure.
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