ISAS Kompakt

• #Cardiovascular diseases
• #Heart damage
• #Interview
• #Pharmacology
• #Stem cells

Laboratory Meets Clinic: Understanding Heart Function with Stem Cells

How can new therapeutic approaches for heart failure be developed more effectively? Stem cell research plays a central role in the HI-FIVE project. In this interview, PD Dr Anna Klinke (Herz- und Diabeteszentrum NRW) talks about her work between the lab and the clinic. She explains how the versatility of stem cells enables heart and vascular cells to be obtained from individual patients' blood and why this is an important step in investigating the specific effects of new active substances.

• #Cardiovascular diseases
• #Heart attack
• #Heart damage
• #Multiomics
• #PhD
• #Proteomics
• #Questionnaire

What are you doing at ISAS, Kevin?

What changes take place in heart muscle cells when a left ventricular assist device is used? ISAS doctoral student Kevin Hau (28) is tackling this question by researching the consequences of heart attacks using various omics analyses.

• #Imaging
• #Interview
• #Lipidomics
• #Lipids
• #Mass spectrometry
• #PhD
• #Research Stay
• #Scholarship

Copenhagen: Different Molecules, New Perspectives?

Felix Hormann is spending three months conducting research at the University of Copenhagen. In this interview, the ISAS doctoral student discusses the new perspective he has gained on his lipid research and his exciting day-to-day life as a scientist in Denmark.

• #Cardiovascular diseases
• #Gender specific health research
• #Heart attack
• #Heart damage

New Perspectives for Heart Failure Therapy

How are new therapeutic approaches being developed to close the gap in the treatment of patients with heart failure? And what knowledge from clinical practice is crucial for this? Prof. Dr Tanja Rudolph provides insights into her daily work as a cardiologist and talks about her role in the translational research project HI-FIVE, and the future of cardiovascular disease therapy.

• #Heart attack
• #Immune cells
• #Immune system
• #Podcast
• #Proteomics
• #Stroke
• #Tumour
• #Young scientists

PODCAST »NACHGEFORSCHT – DIE LIVESCHALTE INS LABOR« Episode 12: Less Is More, at Least When It Comes to the Number of Cells

PhD student Susmita Ghosh talks about her research on neutrophil granulocytes – tiny immune cells that play a role in both defending the body against infections and inflammatory processes. Instead of working with countless cells, the biologist optimises analytical methods to enable meaningful proteome analyses with an extremely small number of cells. Ghosh explains why ‘less is more’ and what this has to do with modern mass spectrometry in episode 12 of the podcast.

What are you doing at ISAS, Nora?

Nora Pauly is writing her doctoral thesis on the consequences of heart attacks at the joint graduate college of Essen University Hospital and ISAS. With the bed-to-bench-to-bed principle, her work in basic research is closely linked to the everyday clinical practice of caring for heart attack patients.