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PhD student Susmita Ghosh talks about her research on neutrophil granulocytes – tiny immune cells that play a role in both defending the body against infections and inflammatory processes. Instead of working with countless cells, the biologist optimises analytical methods to enable meaningful proteome analyses with an extremely small number of cells. Ghosh explains why ‘less is more’ and what this has to do with modern mass spectrometry in episode 12 of the podcast.

Nora Pauly is writing her doctoral thesis on the consequences of heart attacks at the joint graduate college of Essen University Hospital and ISAS. With the bed-to-bench-to-bed principle, her work in basic research is closely linked to the everyday clinical practice of caring for heart attack patients.

How can AI be used optimally in bioimaging research? A team of international researchers and scientists led by Dr Jianxu Chen from ISAS has developed a framework designed to make it easier for biomedical scientists to work with data-centric AI. Using the example of vascular segmentation, the authors of the publication in the journal npj imaging now demonstrate the advantages of the new framework.

How does gut microbiota affect the immune system? Susmita Ghosh conducts research on proteins and immune cells at ISAS. In this interview, the biologist talks about her work and explains how gut flora and the immune system could affect the outcomes of a stroke.

Which factors can activate immune cells after a stroke? This question was investigated by researchers at University Hospital Essen and ISAS. Their work focused on the gut microbiota.

In his doctorate, Dr Ali Ata Tuz researched the causes of immunodeficiency after strokes and was already working closely with ISAS at the time. Following this, he subsequently devoted himself to the behaviour of immune cells in the bioimaging research group at ISAS. In this interview, the physician talks about his path from the clinic to application-oriented basic research.
