Publications

T. Figueiredo W, Prakash R, G. Vieira C, S. Lima D, Raschke H, W. Perez-Lopez O, L.Baptista D, Hergenröder R, Segala M, Bernardi F.

New insights on the electronic factor of the SMSI effect in Pd/TiO2 nanoparticles

Applied Surface Science, Vol. 574, Nr. 151647, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.apsusc.2021.151647

Knitsch R, Alwahsh M, Lambert J, Raschke H, Hergenröder R.

In vitro spatio-temporal NMR metabolomics of living 3D cell models

Analytical Chemistry, Vol. 93, Nr. 40, 2021, P. 13485–13494

Type: Journal article

DOI: /doi.org/10.1021/acs.analchem.1c02221

Borgmeyer M, Coman C, Has C, Schött HF, Li T, Westhoff P, Cheung YFH, Hoffmann N, Yuanxiang P, Behnisch T, Gomes GM, Dumenieu M, Schweizer M, Chocholoušková M, Holčapek M, Mikhaylova M, Kreutz MR, Ahrends R.

Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Cell Reports, Vol. 37, Nr. 1, 2021, P. 109797

Type: Journal article

DOI: /doi.org/10.1016/j.celrep.2021.109797

Migdadi LYH, Lambert J, Telfah A, Hergenröder R, Wöhler C.

Automated Metabolic Assignment: Semi-Supervised Learning in Metabolic Analysis Employing Two Dimensional Nuclear Magnetic Resonance (NMR)

Computational and Structural Biotechnology journal, Vol. 19, 2021, P. 5047–5058

Type: Journal article

DOI: /doi.org/10.1016/j.csbj.2021.08.048

Kohlschmidt N, Elbracht M, Czech AA, Häusler M, Phan V, Töpf A, Huang KT, Bartok A, Eggermann K, Zippel S, Eggermann T, Freier E, Groß C, Lochmüller H, Horvath R, Hajnóczky G, Weis J, Roos A.

Molecular pathophysiology of human MICU1-deficiency

Neuropathology and applied neurobiology, Vol. 47, Nr. 6, 2021, P. 840–855

Type: Journal article

DOI: /doi.org/10.1111/nan.12694

Moreno-Gonzalez D, Castilla-Fernandez D, Vogel P, Niu G, Brandt S, Drees C, García-Reyes JF, Molina-Díaz A, Franzke J.

Evaluation of a novel controlled-atmosphere flexible microtube plasma soft ionization source for the determination of BTEX in olive oil by headspace-gas chromatography/mass spectrometry

Analytica Chimica Acta, Vol. 1179, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.aca.2021.338835

Heestermans M, Naudin C, Mailer RK, Konrath S, Klaetschke K, Jamsa A, Frye M, Deppermann C, Pula G, Kuta P, Friese MA, Gelderblom M, Sickmann A, Preston RJS, Nofer JR, Rose-John S, Butler LM, Salomon O, Stavrou EX, Renne T.

Identification of the factor XII contact activation site enables sensitive coagulation diagnostics

Nature Communications, Vol. 12, Nr. 1, 2021

Type: Journal article

DOI: /doi.org/10.1038/s41467-021-25888-7

Huang J, Zhang P, Solari F, Sickmann A, Garcia A, Jurk K, Heemskerk JWM.

Molecular Proteomics and Signalling of Human Platelets in Health and Disease

International Journal of Molecular Sciences, Vol. 22, Nr. 18, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22189860

Abad C, Minus S, Recknagel S, Jakubowski N, Panne U, Becker-Roß H, Huang MD.

Determination of organic chlorine in water via AlCl derivatization and detection by high-resolution continuum source graphite furnace molecular absorption spectrometry

Analytical Methods, Vol. 13, Nr. 33, 2021, P. 3724–3730

Type: Journal article

DOI: /doi.org/10.1039/D1AY00430A

Hathazi D, Cox D, D'Amico A, Tasca G, Charlton R, Carlier RY, Baumann J, Kollipara L, Zahedi RP, Feldmann I, Deleuze JF, Torella A, Cohn R, Robinson E, Ricci F, Jungbluth H, Fattori F, Boland A, O'Connor E, Horvath R, Barresi R, Lochmüller H, Urtizberea A, Jacquemont ML, Nelson I, Swan LE, Bonne G, Roos A.

INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH

Brain, Vol. 144, Nr. 8, 2021, P. 2427–2442

Type: Journal article

DOI: /doi.org/10.1093/brain/awab133

Unterumsberger R, Beckhoff B, Gross A, Stosnach H, Nowak S, Stenzel YP, Kramer M, von Bohlen A.

A round robin test for total reflection X-ray fluorescence analysis using preselected and well characterized samples

Journal of Analytical Atomic Spectrometry, Vol. 36, Nr. 9, 2021, P. 1933–1945

Type: Journal article

DOI: /doi.org/10.1039/d1ja00103e

Rufo N, Korovesis D, Van Eygen S, Derua R, Garg AD, Finotello F, Vara-Perez M, Rozanc J, Dewaele M, de Witte PA, Alexopoulos LG, Janssens S, Sinkkonen L, Sauter T, Verhelst SHL, Agostinis P.

Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1 alpha kinase inhibitor KIRA6 through HSP60 targeting

Cell Death and Differentiation, 2021

Type: Journal article

DOI: /doi.org/10.1038/s41418-021-00853-5

Beck S, Stegner D, Loroch S, Baig AA, Goeb V, Schumbrutzki C, Eilers E, Sickmann A, May F, Nolte MW, Panousis C, Nieswandt B.

Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents

Journal of Thrombosis and Haemostasis : JTH, 2021

Type: Journal article

DOI: /doi.org/10.1111/jth.15488

Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn LT, Thomalla D, Huelsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP.

MARCKS affects cell motility and response to BTK inhibitors in CLL

Blood, Vol. 138, Nr. 7, 2021, P. 544–556

Type: Journal article

DOI: /doi.org/10.1182/blood.2020009165

Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T.

Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy

European heart journal, Vol. ehab430, 2021

Type: Journal article

DOI: /doi.org/10.1093/eurheartj/ehab430

Hamadneh L, Bahader M, abuarqoub R, Alwahsh M, Alhusban A, Jasim S.

PI3K/AKT and MAPK1 Molecular Changes Preceding Matrix Metallopeptidases Overexpression during Tamoxifen Resistance Development are Correlated to Poor Prognosis in Breast Cancer Patients

BMC Breast Cancer Research, 2021

Type: Journal article

DOI: /doi.org/10.1007/s12282-021-01277-2

Manke MC, Geue S, Coman C, Peng B, Kollotzek F, Münzer P, Walker B, Huber SM, Rath D, Sickmann A, Stegner D, Duerschmied D, Lang F, Nieswandt B, Gawaz M, Ahrends R, Borst O.

ANXA7 Regulates Platelet Lipid Metabolism and Ca2+ Release in Arterial Thrombosis

Circulation Research, Vol. 129, Nr. 4, 2021, P. 494–507

Type: Journal article

DOI: /doi.org/10.1161/CIRCRESAHA.121.319207

Kahler JP, Verhelst SHL.

Phosphinate esters as novel warheads for activity-based probes targeting serine proteases

RSC chemical biology, Vol. 2, Nr. 4, 2021, P. 1285–1290

Type: Journal article

DOI: /doi.org/10.1039/d1cb00117e

Fatangare A, Glässner A, Sachs B, Sickmann A.

Future perspectives on in-vitro diagnosis of drug allergy by the lymphocyte transformation test

Journal of immunological methods, Vol. 495, 2021, P. 113072

Type: Journal article

DOI: /doi.org/10.1016/j.jim.2021.113072

Braun F, Hentschel A, Sickmann A, Marteau T, Hertel S, Foerster F, Prokisch H, Wagner M, Wortmann S, Della Marina A, Koelbel H, Roos A, Schara-Schmidt U.

Muscular and Molecular Pathology Associated with SPATA5 Deficiency in a Child with EHLMRS

International Journal of Molecular Sciences, Vol. 22, Nr. 15, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22157835

Merk V, Speiser E, Werncke W, Esser N, Kneipp J.

pH-Dependent Flavin Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Ultraviolet Resonance Raman (UVRR) Spectra at Intracellular Concentration

Applied Spectroscopy, Vol. 75, Nr. 8, 2021, P. 994–1002

Type: Journal article

DOI: /doi.org/10.1177/00037028211025575

Gazeli O, Lazarou C, Niu G, Anastassiou C, Georghiou GE, Franzke J.

Propagation dynamics of a helium micro-tube plasma

Spectrochimica Acta Part B-Atomic Spectroscopy, Vol. 182, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.sab.2021.106248

Lill JK, Thiebes S, Pohl JM, Bottek J, Subramaniam N, Christ R, Soun C, Gueler F, Zwanziger D, Hoffmann F, von Eggeling F, Bracht T, Sitek B, Hickey MJ, Hofnagel O, Engel DR.

Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga toxin-induced hemolytic uremic syndrome

Kidney international, Vol. 100, Nr. 2, 2021, P. 349–363

Type: Journal article

DOI: /doi.org/10.1016/j.kint.2021.03.039

Kerp H, Hönes GS, Tolstik E, Hönes-Wendland J, Gassen J, Moeller LC, Lorenz K, Führer D.

Protective Effects of Thyroid Hormone Deprivation on Progression of Maladaptive Cardiac Hypertrophy and Heart Failure

Frontiers in cardiovascular medicine, Vol. 8, 2021, P. 683522

Type: Journal article

DOI: /doi.org/10.3389/fcvm.2021.683522

Mohammed Y, Bhowmick P, Michaud SA, Sickmann A, Borchers CH.

Mouse Quantitative Proteomics Knowledgebase

Bioinformatics, Vol. 37, Nr. 13, 2021, P. 1900–1908

Type: Journal article

DOI: /doi.org/10.1093/bioinformatics/btab018

Sanna S, Plaickner J, Holtgrewe K, Wettig VM, Speiser E, Chandola S, Esser N.

Spectroscopic Analysis of Rare-Earth Silicide Structures on the Si(111) Surface

Materials, Vol. 14, Nr. 15, 2021, P. 4104

Type: Journal article

DOI: /doi.org/10.3390/ma14154104

Ok K, Filipovic MR, Michel SLJ.

Targeting Zinc Finger Proteins with Exogenous Metals and Molecules

European journal of inorganic chemistry, 2021

Type: Journal article

DOI: /doi.org/10.1002/ejic.202100402

Walter C, Marada A, Suhm T, Ernsberger R, Muders V, Kücükköse C, Sánchez-Martín P, Hu Z, Aich A, Loroch S, Solari F, Poveda-Huertes D, Schwierzok A, Pommerening H, Matic S, Brix J, Sickmann A, Kraft C, Dengjel J, Dennerlein S, Brummer T, Vögtle FN, Meisinger C.

Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery

Nature Communications, Vol. 12, Nr. 1, 2021

Type: Journal article

DOI: /doi.org/10.1038/s41467-021-24426-9

Tian C, Ahlmann N, Brandt S, Franzke J, Niu G.

Optical characterization of miniature flexible micro-tube plasma (FμTP) ionization source: A dielectric guided discharge

Spectrochimica Acta Part B-Atomic Spectroscopy, Nr. 181, 2021, P. 106222

Type: Journal article

Bahti A, Telfah A, Lambert J, Hergenröder R, Suter D.

Optimal control pulses for subspectral editing in low field NMR

Journal of Magnetic Resonance, Vol. 328, Nr. 1090-7807, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.jmr.2021.106993

Korovesis D, Beard HA, Mérillat C, Verhelst SHL.

Probes for Photoaffinity Labelling of Kinases

ChemBioChem, Vol. 22, Nr. 13, 2021, P. 2206–2218

Type: Journal article

DOI: /doi.org/10.1002/cbic.202000874

Farhat J, Pandey I, Alwahsh M.

Transcending toward Advanced 3D-Cell Culture Modalities

Cells, Vol. 10, Nr. 7, 2021, P. 1657

Type: Journal article

DOI: /doi.org/10.3390/cells10071657

Petrovic D, Kouroussis E, Vignane T, Filipovic MR.

The Role of Protein Persulfidation in Brain Aging and Neurodegeneration

Frontiers in aging neuroscience, Vol. 13, 2021, P. 674135

Type: Journal article

DOI: /doi.org/10.3389/fnagi.2021.674135

Kienle K, Glaser KM, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, Epple MW, Gunzer M, Baumeister R, Tarrant TK, Germain RN, Irimia D, Kastenmüller W, Lämmermann T.

Neutrophils self-limit swarming to contain bacterial growth in vivo

Science, Vol. 372, Nr. 6548, 2021

Type: Journal article

DOI: /doi.org/10.1126/science.abe7729

Castilla-Fernandez D, Moreno-Gonzalez D, García-Reyes JF, Ballesteros E, Molina-Díaz A.

Determination of atropine and scopolamine in spinach-based products contaminated with genus Datura by UHPLC-MS/MS

Food Chemistry, Vol. 347, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.foodchem.2021.129020

Huang J, Swieringa F, Solari F, Provenzale I, Grassi L, De Simone I, Baaten C, Cavill R, Sickmann A, Frontini M, Heemskerk JWM.

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

Scientific reports, Vol. 11, Nr. 1, 2021

Type: Journal article

DOI: /doi.org/10.1038/s41598-021-91661-x

Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM.

Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice

Basic Research in Cardiology, Vol. 116, Nr. 1, 2021, P. 40

Type: Journal article

DOI: /doi.org/10.1007/s00395-021-00881-9

Cheung HYF, Coman C, Westhoff P, Manke M, Sickmann A, Borst O, Gawaz M, Watson SP, Heemskerk JWM, Ahrends R.

Targeted Phosphoinositides Analysis Using High-Performance Ion Chromatography-Coupled Selected Reaction Monitoring Mass Spectrometry

Journal of Proteome Research, Vol. 20, Nr. 6, 2021, P. 3114–3123

Type: Journal article

DOI: /doi.org/10.1021/acs.jproteome.1c00017

Topf A, Pyle A, Griffin H, Schon K, N.N. , N.N. , Sickmann A, Schara-Schmidt U, Hentschel A, Chinnery PF, Koelbel H, Roos A, Horvath R.

Exome reanalysis and proteomic profiling identified TRIP4 as a novel cause of cerebellar hypoplasia and spinal muscular atrophy (PCH1)

European journal of human genetics, 2021

Type: Journal article

DOI: /doi.org/10.1038/s41431-021-00851-8

Sueiro-Olivares M, Scott J, Gago S, Petrovic D, Kouroussis E, Zivanovic J, Yu Y, Strobel M, Cunha C, Thomson D, Fortune-Grant R, Thusek S, Bowyer P, Beilhack A, Carvalho A, Bignell E, Filipovic MR, Amich J.

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

Plos biology, Vol. 19, Nr. 6, 2021, P. e3001247

Type: Journal article

DOI: /doi.org/10.1371/journal.pbio.3001247

Sachs B, Fatangare A, Sickmann A, Glassner A.

Lymphocyte transformation test

Journal of immunological methods, Vol. 493, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.jim.2021.113036

Pfeiffer J, Lorenz K.

Murine models for heart failure: Their creation and applicability to human still require critical and careful considerations

IJC Heart & Vessels, Vol. 34, Nr. 34, 2021, P. 100781

Type: Journal article

DOI: /doi.org/10.1016/j.ijcha.2021.100781

Cirksena K, Hutte HJ, Shcherbakova A, Thumberger T, Sakson R, Weiss S, Jensen LR, Friedrich A, Todt D, Kuss AW, Ruppert T, Wittbrodt J, Bakker H, Buettner FFR.

The C-Mannosylome of Human Induced Pluripotent Stem Cells Implies a Role for ADAMTS16 C-Mannosylation in Eye Development

Molecular & Cellular Proteomics, Vol. 20, 2021, P. 100092

Type: Journal article

DOI: /doi.org/10.1016/j.mcpro.2021.100092

Jender M, Höving S, Novo P, Freier E, Janasek D.

Coupling Miniaturized Free-Flow Electrophoresis to Mass Spectrometry via a Multi-Emitter ESI Interface

Analytical Chemistry, Vol. 93, Nr. 19, 2021, P. 7204 – 7209

Type: Journal article

DOI: /doi.org/10.1021/acs.analchem.1c00200

Rodríguez-Soacha DA, Fender J, Ramírez YA, Collado JA, Muñoz E, Maitra R, Sotriffer C, Lorenz K, Decker M.

"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar " Cis-On" CB 1 R Antagonist

ACS chemical neuroscience, Vol. 12, Nr. 9, 2021, P. 1632–1647

Type: Journal article

DOI: /doi.org/10.1021/acschemneuro.1c00086

Yang J, Mendowicz RJ, Verhelst SHL.

Tagged benzoxazin-4-ones as novel activity-based probes for serine proteases

ChemBioChem, Vol. 22, Nr. 9, 2021, P. 1578–1581

Type: Journal article

DOI: /doi.org/10.1002/cbic.202000848

Wagner M, Sadeck MS, Dybkova N, Mason FE, Klehr J, Firneburg R, Cachorro E, Richter K, Klapproth E, Künzel S, Lorenz K, Heijman J, Dobrev D, El-Armouche A, Sossalla S, Kämmerer S.

Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression

International Journal of Molecular Sciences, Vol. 22, Nr. 9, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22094816

Shevchuk O, Jurak Begonja A, Gambaryan S, Totzeck M, Rassaf T, Huber TB, Greinacher A, Renné T, Sickmann A.

Proteomics

International Journal of Molecular Sciences, Vol. 22, Nr. 9, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22094776

Singh V, Beer A, Kraus A, Mang F, Zhang X, Xue J, Hagemann N, Hermann DM, Gunzer M.

Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs

Brain behavior and immunity, Vol. 94, 2021, P. 458–462

Type: Journal article

DOI: /doi.org/10.1016/j.bbi.2021.01.039

Rhoden A, Friedrich FW, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer BM, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F.

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Redox biology, Vol. 41, 2021, P. 101951

Type: Journal article

DOI: /doi.org/10.1016/j.redox.2021.101951