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ISAS Kompakt
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- #Lipidomics
- #Lipids
- #Mass spectrometry
"Fatty" signatures: How lipid patterns can be used as a diagnostic tool
Microglial cells, the immune cells of the central nervous system, are known for their different appearances. In order to demonstrate this heterogeneity for the first time at the lipid and thus metabolic level for individual cells, a team of researchers has set itself a special analysis goal: Decoding the unique and "fatty" signatures of individual cells.
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- #Lipidomics
- #Mass spectrometry
- #Metabolomics
- #Multiomics
- #Platelets
- #Statement
- #Thrombosis
Thrombocyte Proteome: Tracking down Life-threatening Events in the Bloodstream
Thrombocytes (blood platelets) can link up at lightning speed and block a vessel as a thrombus. Possible consequences include heart attacks or strokes. Scientists at ISAS are therefore looking for molecular markers for platelet activation. In future, this knowledge could help doctors recognise a thrombosis before it occurs and react accordingly.
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- #Cardiovascular diseases
- #Heart attack
- #Heart damage
- #Hormones
- #Pharmacology
- #Stroke
Thyroid hormones: Timers for the heart?
The Collaborative Research Centre "Local Control of Thyroid Hormone Action - LOCOTACT" investigates the local control of the effects of thyroid hormones in organs such as the heart or liver. In order to find new therapeutic approaches for cardiovascular diseases, for example, researchers at ISAS want to know: How does the body control the transport, metabolism and mechanism of action of thyroid hormones in the heart?
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- #Imaging
- #Internship
- #Interview
- #Light sheet fluorescence microscope
- #Microscopy
- #Statement
- #Vocational training
- #Young scientists
From ISAS to Harvard: a special research stay during the PhD programme
The laboratories of the Bioimaging working group at ISAS are currently unusually empty. Two of the doctoral students have left the institute for a several-month research stay in the USA. An Interview with Head of the research group, Prof Dr Anika Grüneboom, ans statements from the two travellers give an insight into the advantages of this for their own scientific careers as well as the entire group's work.
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- #Internship
- #Mass spectrometry
- #Questionnaire
- #Vocational training
- #Young scientists
What are you doing at ISAS, Marcos?
There are almost 1,400 kilometres between Marcos Nadales Neira's home town of Zaragoza in Spain and Dortmund. Why the 18-year-old decided to do an internship at ISAS and what he hopes to gain from his time at the institute, he reports for ISAS Kompakt.
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- #Good scientific practice
- #Questionnaire
What are you doing at ISAS, Yvonne?
What does good scientific practice actually mean? And what are the tasks of a designated ombudsperson? Dr Yvonne Reinders gives an insight into her voluntary work.
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