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"Book a Scientist": Register Now for a Virtual Chat with Researchers

Dortmund, 20th September 2024

Why do we need animal experiments and how can we reduce them? What role does the immune system play in a heart attack? And how does one even become a researcher? Answers to these questions and many more await those interested in science at the "Book a Scientist" event on 15 October 2024, where two ISAS researchers and many other scientists from the Leibniz Association will provide answers to anyone who is curious in virtual one-on-one discussions. Both young people and adults can take part. School groups can also participate.

Book A Scientist. Talking about the world with experts from the Leibniz Association. And understand them. 15 October 2024 10-11:30 and 16-17:30hrs.

"Book a Scientist" is an annual dialogue format of the Leibniz Association. Based on the speed dating principle, interested participants meet Leibniz scientists in 25-minute video calls and ask them what has always interested them about a particular topic. The researchers will be available for brief discussions between 10 and 11.30 am and 4 and 5.30 pm. Whether laypeople or researchers from other disciplines - the format is explicitly aimed at anyone interested in science. The more than 130 topics can be booked via the Leibniz Association (see below).

Two ISAS researchers are taking part this year:

"Why does our immune system overreact after a heart attack - and what does this mean for patients?"

Prof Dr Anika Grüneboom is a biologist who focuses her research at ISAS on the communication of immune cells. She is focussing on two particular cell types, neutrophil granulocytes and macrophages. In order to gain a deep insight into unknown processes in the immune system after a heart attack, the immunologist uses various microscopes to study the behaviour of neutrophils and macrophages in the hearts of mice. Her aim is to use the knowledge gained to identify molecular targets for drugs - and thus pave the way for new heart attack therapies. In addition to animal tissue, Grüneboom's research primarily utilises alternative methods such as cell cultures and patient samples.

Portrait von Prof. Dr. Anika Grüneboom.

Prof Dr Anika Grüneboom is head of the Bioimaging research group and coordinator of the 3D Molecular Pathology research programme at ISAS. The 37-year-old holds the professorship for Experimental Biomedical Imaging at the University of Duisburg-Essen since 2020. Grüneboom is passionate about speaking about her research - whether in front of young people or an expert audience.

© ISAS / Hannes Woidich

Booking: Prof Dr Anika Grüneboom takes part in "Book a Scientist" in the category "Health, Ageing & Nutrition".

"Animal testing - why do we need it and how can we reduce it?"

Prof Dr Matthias Gunzer is a biologist and conducts fundamental research at ISAS and Essen University Hospital. He investigates human and murine (mice) immune cells, more precisely: neutrophil granulocytes. His aim is to elucidate previously poorly understood immunological relationships in the human body. To this end, Gunzer and his team are developing animal models and microscopy tools for analysing neutrophils. They are using these tools to investigate the movement behaviour of neutrophils during tumour therapy, for example. Gunzer works with animal experiments and alternative methods such as cell cultures. But why can't immunologists investigate cancer metastases or strokes in a petri dish? For which medical questions in humans are mice indispensable? How can the number of laboratory animals be reduced? Gunzer provides the answers to these questions in Book a Scientist.

Das Foro zeigt Prof. Dr. Matthias GUnzer im Porträt.

Prof Dr Matthias Gunzer heads the Biospectroscopy Department and the Biofluorescence Research Group at ISAS. He is the director of the Institute for Experimental Immunology and Imaging at the University Hospital Duisburg-Essen. Gunzer has held a professorship at the University of Duisburg-Essen since 2011. The immunologist is an enthusiastic science communicator.

© ISAS / Hannes Woidich

Booking: Prof Dr Matthias Gunzer takes part in "Book a Scientist" in the category "Health, Ageing & Nutrition".

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Further articles

3 Questions for Neele Rottmann

In the lab, Neele Rottmann prepares human and animal samples for mass spectrometry analysis. As part of the HI-FIVE project, she is helping to identify changes at the protein level in heart failure. Why does she spend so much time in the lab working on separations? The technical assistant shares the answer in this interview.

Neele Rottmann is wearing a white lab coat and purple gloves and is operating a mass spectrometry analyser in a laboratory. Next to her is a liquid chromatography system connected to a mass spectrometer via several tubes. There are numerous sample vials on the instrument. As she places a sample into the system, she looks into the camera.

High-tech against Cardiovascular Diseases: 3D Images of Blood Vessels

How do atherosclerotic plaques form in the coronary arteries? At ISAS, researchers are investigating cellular changes in human coronary arteries using techniques such as 3D imaging. During her internship, early-career researcher Leonie Menzel used a light sheet fluorescence microscope to analyse the spatial distribution of individual cells within the tissue. She thereby gained valuable methodological experience for her Master’s thesis.

3 Questions for Lukas Fu

How can AI support the analysis of biomedical images? This was the question Lukas Fu explored during his school internship at ISAS. The 15-year-old also successfully completed his first programming project.

Lukas Fu, a 15-year-old with short black hair. He is wearing glasses and is sitting on a low wall.

Separating Fluorescence Signals Faster and More Precisely with AI

When different fluorescence signals overlap during microscopy, their clear assignment to specific biological structures becomes difficult. To address this common problem, Dr Davide Panzeri is developing AI-based signal separation methods. The biophysicist has been awarded a Marie Skłodowska-Curie Fellowship by the European Union for his promising research project.

Porträt Dr. Davide Panzeri.

Passionate Research, Shaping the Future

How do GRK5 inhibitors work at the cellular level and within the living organism? Biologist Dr Susanne Grund is working with her colleagues at HI-FIVE on a new therapeutic approach for heart failure. In this portrait, she describes what her day-to-day work looks like, balancing research on human stem cells with studies on mice.

ISAS BFF Uploader

What are you doing at ISAS, Theresa?

Why do mice undergo ultrasound examinations of their hearts? What does a typical working day in the lab involve for a technical assistant in the HI-FIVE research project ? And what challenges does the job present? Theresa Pietz provides fascinating insights into her duties, motivations and experiences working with animals.

Study with Heart: A Doctor Bridging Clinic & Laboratory

What is actually happening behind the scenes of a patient trial? Anna Ruzhyna is a clinical research associate who looks after participants with heart failure as part of the HI-FIVE project. She explains how her work helps to develop new therapeutic approaches for the treatment of heart failure.

Laboratory Meets Clinic: Understanding Heart Function with Stem Cells

How can new therapeutic approaches for heart failure be developed more effectively? Stem cell research plays a central role in the HI-FIVE project. In this interview, PD Dr Anna Klinke (Herz- und Diabeteszentrum NRW) talks about her work between the lab and the clinic. She explains how the versatility of stem cells enables heart and vascular cells to be obtained from individual patients' blood and why this is an important step in investigating the specific effects of new active substances.