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- #AI
- #Infection
- #Machine learning
Machine learning for early warning systems in a clinical setting?
Physicians often find themselves racing against time. In most cases, the faster treatment can be provided, the better it is for patients. The diagnosis should therefore be made as early as possible. This is where artificial intelligence could come into play. An interdisciplinary team of researchers has investigated the extent to which machine learning models are suitable for analysing clinical data - for example, to predict sepsis (blood poisoning) earlier than currently possible.
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- #Cell culture
- #Clearing
- #Imaging
- #Immune system
- #Infection
- #Light sheet fluorescence microscope
- #Science communication
- #Young scientists
Red Alert: Students Research the Immune System at Girls' Day
What alarm bells ring when our immune system is under attack? Why do infections occur even without external invaders? And what do a heart attack and a cold have in common? These are just some of the questions that 12 schoolgirls got to the bottom of during this year's Girls' Day at ISAS.
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- #Ageing research
- #Persulfidation
Hydrogen Sulfide: The Surprising Molecule That Regulates Life's Vital Functions & Fights Aging
Hydrogen sulfide is considered highly toxic. Nevertheless, the foul-smelling gas fulfills many vital functions in our cells. As a gasotransmitter, for example, it can transmit signals within and between cells. But hydrogen sulfide also plays an important role in the oxygen supply in the blood – as researchers led by Dr habil Miloš Filipović at ISAS recently discovered.
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- #AI
- #Deep learning
- #Image analysis
- #Immune cells
- #Microscopy
- #Software
- #Sustainability
New “Green” Microscopy: Less Electricity, but More Information on Immune Cells in Return
Advanced technologies, such as high-resolution microscopes, produce large amounts of data. And these again consume large amounts of electricity. In addition, there are refrigerators for samples, fume cupboards and small technical devices. While ISAS is upgrading to become greener, researchers at the institute are already working on methods to make microscopy more energy-efficient in general.
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- #Cirrhosis of the liver
- #Imaging
- #Immune cells
- #Immune system
- #Neutrophils
Cirrhosis of the Liver: Migrating Immune Cells Act as an Early Warning System
The life expectancy of patients with liver cirrhosis depends crucially on the occurrence of disease-associated complications, such as infections. Until now, however, an ability to predict these at an early stage has been lacking. A problem, often hindering doctors from administering antibiotics or even performing a liver transplant in time. Researchers at ISAS led by Prof Dr Matthias Gunzer therefore investigated the question: Could the mobility of certain immune cells be the decisive indicator of an impending deterioration in health?
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- #Autoimmune diseases
- #Interview
- #Mass spectrometry
- #Neurology
- #Proteomics
3 Questions for… Dr Christopher Nelke
As a participant in the Clinician Scientist programme and physician at the Clinic for Neurology at Düsseldorf University Hospital (Universitätsklinikum Düsseldorf, UKD), Dr Christopher Nelke researches neuromuscular diseases. In this interview, he talks about his two-week guest stay at ISAS and the challenges that arise between the hospital bed and research.
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