ISAS Kompakt

• #Animal models
• #Heart attack
• #Imaging
• #Immune cells
• #Immune system
• #Science communication
• #Stroke

"Book a Scientist": Register Now for a Virtual Chat with Researchers

The format "Book a Scientist" offers those interested in science the opportunity to book individual appointments with researchers within the Leibniz Association. Among them are two ISAS researchers. Their topics are "overzealous" immune cells after a heart attack and animal experiments and their alternatives.

• #AI
• #Microscopy
• #Science communication
• #Young scientists

Fascinating Insights: Virtual World in the Classroom

What actually is reality? How do we perceive our environment? And how can augmented reality support researchers in their work? Along with class 3a of the Don Bosco elementary school in Bochum, two ISAS researchers explored these questions.

Protein interaction paralyses a young patient

Two mutations in the genetic material of a boy lead to the rare neuromuscular disease NEDHFBA. Investigations of the young patient's samples by researchers at Essen University Hospital and ISAS shed light on the previously unrecognized mechanisms behind the symptoms: Proteins influence the development of the rare disease.

• #Interview
• #Lipidomics
• #Lipids
• #Mass spectrometry

"We want to improve the fundamental understanding of disease models"

Why is it exciting to decode the lipid signature of individual cells? And which cell type is particularly suitable for allowing this process? Prof Dr Sven Heiles gives the answers in an interview.

• #Lipidomics
• #Lipids
• #Mass spectrometry

"Fatty" signatures: How lipid patterns can be used as a diagnostic tool

Microglial cells, the immune cells of the central nervous system, are known for their different appearances. In order to demonstrate this heterogeneity for the first time at the lipid and thus metabolic level for individual cells, a team of researchers has set itself a special analysis goal: Decoding the unique and "fatty" signatures of individual cells.

• #Lipidomics
• #Mass spectrometry
• #Metabolomics
• #Multiomics
• #Platelets
• #Statement
• #Thrombosis

Thrombocyte Proteome: Tracking down Life-threatening Events in the Bloodstream

Thrombocytes (blood platelets) can link up at lightning speed and block a vessel as a thrombus. Possible consequences include heart attacks or strokes. Scientists at ISAS are therefore looking for molecular markers for platelet activation. In future, this knowledge could help doctors recognise a thrombosis before it occurs and react accordingly.