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Biomedical Image Analysis with AI

Dr Jianxu Chen is taking up a professorship in AI for Biomedical Analysis at the University of Duisburg-Essen. With his research group at ISAS, he is developing AI methods that can be used to comprehensively analyse enormous quantities of complex microscopy images.

It's What's Inside That Counts: Neutrophils Form Distinct Subtypes

Neutrophils can be divided into two distinct subgroups with completely different functions. The surface protein CD177 plays a decisive role in this. For the first time, researchers from the Faculty of Medicine at the University of Duisburg-Essen and ISAS have been able to demonstrate, using a new integrated proteomics and lipidomics analysis, that the molecular signatures in CD177-defined neutrophils differ significantly from one another. The presence of this surface protein has implications for disease progression, for example in head and neck tumours.

New Drug Candidates for the Treatment of Heart Failure

Researchers from North Rhine-Westphalia are working on a new therapeutic approach for the treatment of heart failure as part of the recently launched HI-FIVE project. They are developing active substances that specifically inhibit an important enzyme with the aim of closing gaps in the care of patients with heart failure.