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The research programmes of ISAS pursue the development of various analytical methods to support cross-scale multi-parameter analysis in health research. The objective of this is to address the complex challenges in relation to analytics for personalised medicine (precision medicine).
The three research programmes of the institute interlock with one another owing to the many scientific and technological questions. The synergies resulting from the interdisciplinary collaboration benefits the research projects within a programme. Combining complementary analytical methods plays a central role in the development of new multi-method concepts for health research. In this context the focus is always on the application-specific use of analytics.
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The research programmes focus on: clarifying disease mechanisms and identifying possible treatment approaches – including application reference for subsequent pre-clinical research in both cases; identification and detection of diagnostic, prognostic and therapeutic markers; location- and time-resolved, ideally in-vivo representation of processes, from the molecular to the cellular level; non-invasive and non-destructive analysis methods.
Research Programmes
Publications
Journal of Applied Polymer Science, Vol. 141, No. 17, 2024
Ahmad AA, Al-Bataineh QM, Bani-Salameh AA, Al Omari RH, Telfah A.
Self-cleaning antireflected surfaces based on treated PEO/SiO2 nanocomposite films
https://doi.org/10.1002/app.55275
Biointerphases, Vol. 91, 2024
Weintraut T, Heiles S, Gerbig D, Henss A, Junck J, Düring R, Rohnke M.
Lipid-related ion suppression on the herbicide atrazine in earthworm samples in ToF-SIMS and matrix-assisted laser desorption ionization mass spectrometry imaging and the role of gas-phase basicity
https://doi.org/10.1116/6.0003437
Journal of Applied Polymer Science, Vol. 141, No. 14, 2024
Telfah A, Abu-Zurayk R, Al-Bataineh QM, Tavares CJ, Foadian F, Etzkorn J.
Optical and electrical analysis of polyethylene oxide/disodium hexachloroplatinate complex composite films
https://doi.org/10.1002/app.54980
3D Printing and Additive Manufacturing, 2024
Höving S, Akermann M, Schiller A, Franzke J, Schwendemann D, Brandt S.
Functionalization of Cyclic Olefin Copolymer for Enhanced Electrical Conductivity in Material Extrusion 3D-Printing: Potential Applications in Laboratory Environments and Small-Scale Experiments
https://doi.org/10.1089/3dp.2023.0304
Geroscience, 2024
Panagaki T, Janickova L, Petrovic D, Zuhra K, Ditrói T, Jurányi EP, Bremer O, Ascençao K, Philipp TM, Nagy P, Filipovic MR, Szabo C.
Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine β-synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy
https://doi.org/10.1007/s11357-024-01146-8
Advanced Materials Interfaces, Vol. 2024, No. 2301073, 2023
Neubert TJ, Rösicke F, Hinrichs K, Nickel N, Rappich J.
Quantum dot modification of large area graphene surfaces via amide bonding
https://doi.org/10.1002/admi.202301073
Analytical Chemistry, Vol. 96, No. 13, 2024, P. 5289-5297
Bouza M, Foest D, Brandt S, García-Reyes JF, Franzke J.
Enhanced Compound Analysis Using Reactive Paper Spray Mass Spectrometry: Leveraging Schiff Base Reaction for Amino Acid Detection
https://doi.org/10.1021/acs.analchem.4c00215
Applied Surface Science, Vol. 649, 2024
Al-Bataineh QM, Telfah AD, Tavares CJ, Hergenröder R.
Wide-field surface plasmon resonance microscope based on polyethylene oxide/polyacrylic acid brushes
https://doi.org/10.1016/j.apsusc.2023.159189