When blood starts flowing again after a heart attack, it can literally flood the affected heart muscle cells with oxygen and nutrients and thus cause secondary damage. The DFG-funded research training group ‘TCI repAMI’ at the University Hospital Essen and ISAS is investigating how immune cells, blood vessel cells and heart muscle cells interact in this process. Clinical and research experts are working together in tandem teams in eleven sub-projects to provide interdisciplinary training for a total of 33 doctoral students.
The European Union is funding the NUCLEAR PhD training network with the aim of training young scientists in the fields of metabolic regulation of genome function and cell identity in the context of stem cell biology and cancer research. Twelve partner organisations, including ISAS, are participating in NUCLEAR, pooling their expertise in stem cell biology, precision nutrition, mass spectrometry and drug development, among other areas.
In order to treat anaemia more effectively, researchers in the »NephrESA« project are developing a computer model which can be used to determine the risks and prognoses of the medication for each individual affected.
In the »Targeted & Non-Targeted Metabolomics« project, NMR spectroscopy is used for both targeted and non-targeted metabolome analyses.
At ISAS, scientists in the subproject »Phagocytic crosstalk between neutrophils and macrophages« investigate how immune cells of the type of phagocytes – in specific neutrophil granulocytes and macrophages – communicate with one another.