Skip to content

Adriana Schneider Aims to Make Proteome Analyses More Efficient

Dortmund, 1st September 2021

Gaining more practical experience in science, that is Adriana Schneider’s goal. When the master’s student (bioengineering) learnt about ISAS in a lecture at TU Dortmund University, she decided to write her thesis here. Since November 2020, the japan-loving 30-year-old has been part of the Proteomics working group. She spends six to eight hours a day working in the laboratory.

Schneider is working on optimising the analysis of biological samples. For her master’s thesis, she researches methods of proteome analyses based on the connection of liquid chromatography and mass spectrometry (LC-MS).

Fast analysis & a high sample throughput

As high throughput is important for the analysis of clinical samples and in pharmaceutical research, Schneider wants to figure out which combination of LC-MS-methods and acquisition times provides the highest quality results with the shortest possible measurement times. For this, she considers all steps of the analysis: preparing the samples, handling and maintaining the LC-MS systems and evaluating the results are part of the junior researcher’s everyday work. Finally, she examines the analytical depth, meaning the quality, of the data obtained and checks whether the results are reproducible. Through her work, she hopes to help increase sample throughput in clinical and biomedical research. Schneider aims to submit her thesis in the summer of 2021. After that, the Dortmund researcher would not only like to broaden her Japanese language skills but also to continue working in the field of bioanalytics.

(Cheyenne Peters)

Ein Foto von Adriana Schneider im Labor.

Adriana Schneider is regularly in the laboratory due to her master’s thesis. There the 30 year old knows every move.

© ISAS

Share

Further articles

Passionate Research, Shaping the Future

How do GRK5 inhibitors work at the cellular level and within the living organism? Biologist Dr Susanne Grund is working with her colleagues at HI-FIVE on a new therapeutic approach for heart failure. In this portrait, she describes what her day-to-day work looks like, balancing research on human stem cells with studies on mice.

ISAS BFF Uploader

What are you doing at ISAS, Theresa?

Why do mice undergo ultrasound examinations of their hearts? What does a typical working day in the lab involve for a technical assistant in the HI-FIVE research project ? And what challenges does the job present? Theresa Pietz provides fascinating insights into her duties, motivations and experiences working with animals.

Study with Heart: A Doctor Bridging Clinic & Laboratory

What is actually happening behind the scenes of a patient trial? Anna Ruzhyna is a clinical research associate who looks after participants with heart failure as part of the HI-FIVE project. She explains how her work helps to develop new therapeutic approaches for the treatment of heart failure.

Laboratory Meets Clinic: Understanding Heart Function with Stem Cells

How can new therapeutic approaches for heart failure be developed more effectively? Stem cell research plays a central role in the HI-FIVE project. In this interview, PD Dr Anna Klinke (Herz- und Diabeteszentrum NRW) talks about her work between the lab and the clinic. She explains how the versatility of stem cells enables heart and vascular cells to be obtained from individual patients' blood and why this is an important step in investigating the specific effects of new active substances.

What are you doing at ISAS, Kevin?

What changes take place in heart muscle cells when a left ventricular assist device is used? ISAS doctoral student Kevin Hau (28) is tackling this question by researching the consequences of heart attacks using various omics analyses.

Kevin Hau is wearing a white coat bearing the ISAS logo. He is standing next to a microscope in a laboratory. In the lower left corner of the image, a computer screen can be seen. Open on the monitor is a microscopic image of reddish tissue.

Copenhagen: Different Molecules, New Perspectives?

Felix Hormann is spending three months conducting research at the University of Copenhagen. In this interview, the ISAS doctoral student discusses the new perspective he has gained on his lipid research and his exciting day-to-day life as a scientist in Denmark.

Felix Hormann is standing at a crossroads. In the background, there is a traffic sign with writing in Danish.

New Perspectives for Heart Failure Therapy

How are new therapeutic approaches being developed to close the gap in the treatment of patients with heart failure? And what knowledge from clinical practice is crucial for this? Prof. Dr Tanja Rudolph provides insights into her daily work as a cardiologist and talks about her role in the translational research project HI-FIVE, and the future of cardiovascular disease therapy.

PODCAST »NACHGEFORSCHT – DIE LIVESCHALTE INS LABOR« Episode 12: Less Is More, at Least When It Comes to the Number of Cells

PhD student Susmita Ghosh talks about her research on neutrophil granulocytes – tiny immune cells that play a role in both defending the body against infections and inflammatory processes. Instead of working with countless cells, the biologist optimises analytical methods to enable meaningful proteome analyses with an extremely small number of cells. Ghosh explains why ‘less is more’ and what this has to do with modern mass spectrometry in episode 12 of the podcast.
Return
To the top