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Advancing Analytics

We develop and combine technologies into four-dimensional analytical methods for health research. Our goal: With our analytics for precision medicine, we want to contribute to optimising the prevention, diagnosis and therapy of various diseases.

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Research Programmes

In our three programmes, we conduct research on various interdisciplinary projects. In one of our research programmes, for example, we combine analytical procedures and develop multi-method concepts in order to elucidate disease mechanisms and identify potential therapeutic approaches - always with a clear application purpose for the following preclinical research.

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ISAS Kompakt

10th July 2024

University Professorship for „Artificial Intelligence for Biomedical Analytics“

ISAS and the University of Duisburg-Essen are strengthening their ongoing collaboration with a further professorship based on the Jülich model. Applications are possible until 18 August 2024.

5th July 2024

 Thyroid hormones: Timers for the heart?

The Collaborative Research Centre "Local Control of Thyroid Hormone Action - LOCOTACT" investigates the local control of the effects of thyroid hormones in organs such as the heart or liver. In order to find new therapeutic approaches for cardiovascular diseases, for example, researchers at ISAS want to know: How does the body control the transport, metabolism and mechanism of action of thyroid hormones in the heart?

Videograf André Zelck (rechts im Bild) begleitet die Doktorandin Stefanie Dörr (Kardiovaskuläre Pharmakologie) bei ihrer Arbeit am Echokardiographiegerät.
26th June 2024

From ISAS to Harvard: a special research stay during the PhD programme

The laboratories of the Bioimaging working group at ISAS are currently unusually empty. Two of the doctoral students have left the institute for a several-month research stay in the USA. An Interview with Head of the research group, Prof Dr Anika Grüneboom, ans statements from the two travellers give an insight into the advantages of this for their own scientific careers as well as the entire group's work.

Flora Weber und Darleen Hüser stehen gemeinsam vor der Gordon Hall auf dem Harvard Gelände. Flora Weber and Darleen Hüser stand together in front of Gordon Hall on the Harvard campus.
19th June 2024

What are you doing at ISAS, Marcos?

There are almost 1,400 kilometres between Marcos Nadales Neira's home town of Zaragoza in Spain and Dortmund. Why the 18-year-old decided to do an internship at ISAS and what he hopes to gain from his time at the institute, he reports for ISAS Kompakt.

Marcos Nadales Neira stands in the laboratory with a pipette in his hand.
6th June 2024

What are you doing at ISAS, Yvonne?

What does good scientific practice actually mean? And what are the tasks of a designated ombudsperson? Dr Yvonne Reinders gives an insight into her voluntary work.

Portrait von Dr. Yvonne Reinders.
23rd May 2024

Machine learning for early warning systems in a clinical setting?

Physicians often find themselves racing against time. In most cases, the faster treatment can be provided, the better it is for patients. The diagnosis should therefore be made as early as possible. This is where artificial intelligence could come into play. An interdisciplinary team of researchers has investigated the extent to which machine learning models are suitable for analysing clinical data - for example, to predict sepsis (blood poisoning) earlier than currently possible.

Portrait von Prof. Dr. Robert Heyer.
8th May 2024

Red Alert: Students Research the Immune System at Girls' Day

What alarm bells ring when our immune system is under attack? Why do infections occur even without external invaders? And what do a heart attack and a cold have in common? These are just some of the questions that 12 schoolgirls got to the bottom of during this year's Girls' Day at ISAS.

Das Bild zeigt einen Teil der Schülerinnen zusammen mit Luisa Röbisch, Dr. Anika Grüneboom und Dr. Christiane Stiller, während sie im Labor stehen und in die Kamera schauen.
2nd May 2024

Hydrogen Sulfide: The Surprising Molecule That Regulates Life's Vital Functions & Fights Aging

Hydrogen sulfide is considered highly toxic. Nevertheless, the foul-smelling gas fulfills many vital functions in our cells. As a gasotransmitter, for example, it can transmit signals within and between cells. But hydrogen sulfide also plays an important role in the oxygen supply in the blood – as researchers led by Dr habil Miloš Filipović at ISAS recently discovered.

Porträt Dr. habil. Miloš Filipović.
28th March 2024

New “Green” Microscopy: Less Electricity, but More Information on Immune Cells in Return

Advanced technologies, such as high-resolution microscopes, produce large amounts of data. And these again consume large amounts of electricity. In addition, there are refrigerators for samples, fume cupboards and small technical devices. While ISAS is upgrading to become greener, researchers at the institute are already working on methods to make microscopy more energy-efficient in general.

Das Bild zeigt eine schematische Darstellung der Datenverarbeitung in der Mikroskopie.
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Publications

Physica B: Condensed Matter, Vol. 685, 2024

Al-Bataineh QM, Ahmad AA, Migdadi AB, Bahti A, Telfah A.

Plasmon-exciton interactions in ZnO/AuNPs heterostructure film for high photoconductivity

https://doi.org/10.1016/j.physb.2024.415970

Analytical and Bioanalytical Chemistry, 2024

Speicher L, Song H, Ahlmann N, Foest D, Höving S, Brandt S, Niu G, Franzke J, Tian C.

Soft ionization mechanisms in flexible µ-tube plasma-from FµTP to closed µ-tube plasma

https://doi.org/10.1007/s00216-024-05420-8

Talanta, Vol. 274, 2024

García-Martínez J, Caño-Carrillo I, Gilbert-López B, Bouza M, Beneito-Cambra M, Franzke J, Molina-Díaz A, García-Reyes JF.

Miniaturized flexible micro-tube plasma ionization source for the effective ionization of non-easily ionizable pesticides in food with liquid chromatography/mass spectrometry

https://doi.org/10.1016/j.talanta.2024.126011

Springer New York, Vol. 2820, 2024, P. 99-113

Heyer R, Schallert K, Briza M, Benndorf D.

Metaproteomic Analysis of Biogas Plants: A Complete Workflow from Lab to Bioinformatics

ISBN: 978-1-0716-3912-2

https://doi.org/10.1007/978-1-0716-3910-8_10

Scientific Reports, Vol. 14, No. 1, 2024, P. 14806

Al-Wahsh MI, Nimer RM, Dahabiyeh LA, Hamadneh L, Hasan A, Alejel R, Hergenröder R.

NMR-based metabolomics identification of potential serum biomarkers of disease progression in patients with multiple sclerosis

https://doi.org/10.1038/s41598-024-64490-x

Journal of Materials Science: Materials in Electronics, Vol. 35, No. 17, 2024

Al-Sawalmih A, Al-Bataineh QM, Abu-Zurayk R, Tavares CJ, Etzkorn J, Foadian F, Telfah A.

Optical, electrical and structural properties of iron doped zinc oxide nanostructures

https://doi.org/10.1007/s10854-024-12826-8

Journal of the American Society for Mass Spectrometry, 2024

Höving S, Schomacher J, Schiller A, Franzke J.

Setting the Separation Factor α for Ketone Monomers and Dimers by the Use of Different Drift Gases

https://doi.org/10.1021/jasms.4c00215

Journal of Imaging Informatics in Medicine, 2024

Krieger K, Egger J, Kleesiek J, Gunzer M, Chen J.

Multisensory Extended Reality Applications Offer Benefits for Volumetric Biomedical Image Analysis in Research and Medicine

https://doi.org/10.1007/s10278-024-01094-x

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