Publikationen

Kohlschmidt N, Elbracht M, Czech AA, Häusler M, Phan V, Töpf A, Huang KT, Bartok A, Eggermann K, Zippel S, Eggermann T, Freier E, Groß C, Lochmüller H, Horvath R, Hajnóczky G, Weis J, Roos A.

Molecular pathophysiology of human MICU1-deficiency

Neuropathology and applied neurobiology, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1111/nan.12694

Dalal PJ, Sullivan DP, Weber EW, Sacks DB, Gunzer M, Grumbach IM, Heller Brown J, Muller WA.

Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration

Journal of Experimental Medicine, Bd. 218, Nr. 1, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1084/jem.20192378

Drepper F, Biernat J, Kaniyappan S, Meyer HE, Mandelkow EM, Warscheid B, Mandelkow E.

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

Journal of Biological Chemistry, Bd. 295, Nr. 52, 2020, S. 18213–18225

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1074/jbc.RA120.015882

Verhelst SHL, Bonger KM, Willems LI.

Bioorthogonal Reactions in Activity-Based Protein Profiling

Molecules, Bd. 25, Nr. 24, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/molecules25245994

Korovesis D, Rufo N, Derua R, Agostinis P, Verhelst SHL.

Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor

ACS Chemical Biology, Bd. 15, Nr. 12, 2020, S. 3106–3111

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acschembio.0c00802

Danne-Rasche N, Rubenzucker S, Ahrends R.

Uncovering the complexity of the yeast lipidome by means of nLC/NSI-MS/MS

Analytica Chimica Acta, Bd. 1140, 2020, S. 199–209

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.aca.2020.10.012

Hamouda NN, Van den Haute C, Vanhoutte R, Sannerud R, Azfar M, Mayer R, Cortés Calabuig �, Swinnen JV, Agostinis P, Baekelandt V, Annaert W, Impens F, Verhelst SHL, Eggermont J, Martin S, Vangheluwe P.

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

Journal of Biological Chemistry, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1074/jbc.RA120.013908

van Geffen JP, Swieringa F, van Kuijk K, Tullemans BME, Solari F, Peng B, Clemetson KJ, Farndale RW, Dubois LJ, Sickmann A, Zahedi RP, Ahrends R, Biessen EAL, Sluimer JC, Heemskerk JWM, Kuijpers MJE.

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

Scientific reports, Bd. 10, Nr. 1, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41598-020-78522-9

Gunzer M, Thornton CR, Beziere N.

Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis

Journal of fungi, Bd. 6, Nr. 4, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/jof6040338

van de Plassche MAT, Barniol-Xicota M, Verhelst SHL.

Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2

ChemBioChem, 2020, S. 3383–3388

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/cbic.202000371

Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernández-Calvo G, Khoyratty TE, van Grinsven E, González-Hernández S, Nicolás-Ávila J�, Vicanolo T, Maccataio A, Benguría A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martín-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sánchez-Cabo F, Nistal-Villán E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A.

Co-option of Neutrophil Fates by Tissue Environments

Cell, Bd. 183, Nr. 5, 2020, S. 1282–1297.e18

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.cell.2020.10.003

Ashwood C, Bittremieux W, Deutsch E, Doncheva N, Dorfer V, Gabriels R, Gorshkov V, Gupta S, Jones AR, Käll L, Kopczynski D, Lane L, Lautenbacher L, Legeay M, Locard-Paulet M, Mesuere B, Perez-Riverol Y, Netz E, Pfeuffer J, Sachsenberg T, Salz R, Samaras P, Schiebenhoefer H, Schmidt T, Schwämmle V, Soggiu A, Uszkoreit J, Van Den Bossche T, Van Puyvelde B, Van Strien J, Verschaffelt P, Webel H, Willems S.

Proceedings of the EuBIC-MS 2020 Developers’ Meeting

EuPA Open Proteomics, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.euprot.2020.11.001

Rassaf T, Totzeck M, Mahabadi AA, Hendgen-Cotta UB, Korste S, Settelmeier S, Luedike P, Dittmer U, Herbstreit F, Brenner T, Klingel K, Hasenberg M, Walkenfort B, Gunzer M, Schlosser T, Weymann A, Kamler M, Schmack B, Ruhparwar A.

Ventricular assist device for a coronavirus disease 2019-affected heart

ESC heart failure, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/ehf2.13120

Chakrabarty S, Verhelst SHL.

Controlled Inhibition of Apoptosis by Photoactivatable Caspase Inhibitors

Cell Chemical Biology, Bd. 27, Nr. 11, 2020, S. 1434–1440.e10

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.chembiol.2020.08.001

Usfoor Z, Kaufmann K, Rakib ASH, Hergenröder R, Shpacovitch V.

Features of Sizing and Enumeration of Silica and Polystyrene Nanoparticles by Nanoparticle Tracking Analysis (NTA)

Sensors, Bd. 20, Nr. 22, 2020

Type: Zeitschriftenbeitrag

Furchner A, Kratz C, Hinrichs K.

Laser-IR-Ellipsometrie für die Oberflächenanalytik

GIT Labor-Fachzeitschrift, Bd. 2020, Nr. 11, 2020, S. 36–38

Type: Zeitschriftenbeitrag

Kyselova A, Siragusa M, Anthes J, Solari F, Loroch S, Zahedi RP, Walter U, Fleming I, Randriamboavonjy V.

Cyclin Y Is Expressed in Platelets and Modulates Integrin Outside-in Signaling

International Journal of Molecular Sciences, Bd. 21, Nr. 21, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/ijms21218239

Volz J, Kusch C, Beck S, Popp M, Vögtle T, Meub M, Scheller I, Heil HS, Preu J, Schuhmann MK, Hemmen K, Premsler T, Sickmann A, Heinze KG, Stegner D, Stoll G, Braun A, Sauer M, Nieswandt B.

BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation

The Journal of Clinical Investigation, Bd. 130, Nr. 11, 2020, S. 6064–6079

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1172/JCI136457

Knodel A, Foest D, Brandt S, Ahlmann N, Marggraf U, Gilbert López B, Franzke J.

Detection and Evaluation of Lipid Classes and Other Hydrophobic Compounds Using a Laser Desorption/Plasma Ionization Interface

Analytical Chemistry, Bd. 2020, 2020

Type: Zeitschriftenbeitrag

Jarmusch SA, Feldmann I, Blank-Landeshammer B, Cortés-Albayay C, Castro JF, Andrews B, Asenjo JA, Sickmann A, Ebel R, Jaspars M.

Cutting the Gordian knot: early and complete amino acid sequence confirmation of class II lasso peptides by HCD fragmentation

The Journal of Antibiotics, Bd. 73, Nr. 11, 2020, S. 772–779

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41429-020-00369-z

Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A.

The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets

Journal of Thrombosis and Haemostasis : JTH, Bd. 18, Nr. 11, 2020, S. 3002–3012

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1111/jth.15028

Beneito-Cambra M, Gilbert-López B, Moreno-González D, Bouza M, Franzke J, García-Reyes JF, Molina-Díaz A.

Ambient (desorption/ionization) mass spectrometry methods for pesticide testing in food

Analytical Methods, Bd. 12, Nr. 40, 2020, S. 4831–4852

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1039/d0ay01474e

Sims MC, Mayer L, Collins J, Bariana T, Megy K, Lavenu-Bombled C, Seyres D, Kollipara L, Burden F, Greene D, Lee D, Rodriguez-Romera A, Alessi MC, Astle WJ, Bahou W, Bury L, Chalmers E, Da Silva R, De Candia E, Deevi SVV, Farrow S, Gomez K, Grassi L, Greinacher A, Gresele P, Hart DP, Hurtaud MF, Kelly A, Kerr R, Le Quellec S, Leblanc TM, Leinøe EB, Mapeta RP, McKinney H, Michelson AD, Morais S, Nugent DJ, Papadia S, Park SJ, Pasi J, Podda GM, Poon MC, Reed R, Sekhar M, Shalev H, Sivapalaratnam S, Steinberg-Shemer O, Stephens JC, Tait RC, Turro E, Wu JK, Zieger BMH, Kuijpers TW, Whetton AD, Sickmann A, Freson K, Downes K, Erber W, Frontini M, Nurden P, Ouwehand WH, Favier R, Guerrero JA.

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome

Blood, Bd. 136, Nr. 17, 2020, S. 1956–1967

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1182/blood.2019004776

Hagemann N, Mohamud Yusuf A, Martiny C, Zhang X, Kleinschnitz C, Gunzer M, Kolesnick R, Gulbins E, Hermann DM.

Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia

Basic Research in Cardiology, Bd. 115, Nr. 6, 2020, S. 64

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s00395-020-00823-x

Vanhoutte R, van de Plassche MAT, Verhelst SHL.

Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2

Journal of Medicinal Chemistry, Bd. 63, Nr. 20, 2020, S. 11845–11853

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.jmedchem.0c01043

Knorrscheidt A, Püllmann P, Schell E, Homann D, Freier E, Weissenborn MJ.

Identification of novel unspecific peroxygenase chimeras and unusual YfeX axial heme ligand by a versatile high-throughput GC-MS approach

ChemCatChem, Bd. 12, Nr. 19, 2020, S. 4788–4795

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/cctc.202000618

Hoffmann N, Kopczynski D, Al Machot F, Schwudke D, Miranda Ackermann J, Shevchenko A, Ahrends R.

Lipidomics – How Lipids Control Blood Coagulation

2020

Reihe: DATA ANALYSIS FOR INSIGHTS INTO COMPLEX BIOLOGICAL SYSTEMS

Type: Buchbeitrag

Hack T, Bertram S, Blair H, Borger V, Busche G, Denson L, Fruth E, Giebel B, Heidenreich O, Klein-Hitpass L, Kollipara L, Sendker S, Sickmann A, Walter C, von Neuhoff N, Hanenberg H, Reinhardt D, Schneider M, Rasche M.

Exposure of patient-derived mesenchymal stromal cells to TGFB1 supports fibrosis induction in a pediatric acute megakaryoblastic leukemia model

Molecular Cancer Research, Bd. 18, Nr. 10, 2020, S. 1603–1612

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1158/1541-7786.MCR-20-0091

Metzger P, Kirchleitner SV, Boehmer DFR, Hörth C, Eisele A, Ormanns S, Gunzer M, Lech M, Lauber K, Endres S, Duewell P, Schnurr M, König LM.

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

Cancer Immunology, Immunotherapy, Bd. 69, Nr. 10, 2020, S. 2101–2112

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s00262-020-02605-9

Stein V, Blank-Landeshammer B, Muentjes K, Maerker R, Teichert I, Feldbruegge M, Sickmann A, Kueck U.

The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes

Plos genetics, Bd. 16, Nr. 9, 2020, S. e1008819

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1371/journal.pgen.1008819

Kopczynski D, Hentschel A, Coman C, Schebb NH, Hornemann T, Mashek D, Hartung NM, Shevchuk O, Schött HF, Lorenz K, Torta F, Burla B, Zahedi RP, Sickmann A, Kreutz MR, Ejsing C, Medenbach J, Ahrends R.

Simple targeted assays for metabolic pathways and signaling: a powerful tool for targeted proteomics

Analytical Chemistry, Bd. 92, Nr. 20, 2020, S. 13672–13676

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.analchem.0c02793

Mailer RK, Allende M, Heestermans M, Schweizer M, Deppermann C, Frye M, Pula G, Odeberg J, Gelderblom MP, Rose-John S, Sickmann A, Blankenberg S, Huber TB, Kubisch C, Maas C, Gambaryan S, Firsov D, Stavrou EX, Butler L, Renné T.

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate

Blood, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1182/blood.2019004617

Koenig M, Trouillet V, Welle A, Hinrichs K, Lahann J.

Molecular Changes in Vapor-based Polymer Thin Films Assessed by Characterization of Swelling Properties of Amine-Functionalized Poly-p-xylylene

Macromolecular Chemistry and Physics, Bd. 221, Nr. 19, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/macp.202000213

Kahler JP, Lenders S, van de Plassche MAT, Verhelst SHL.

Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction

Bioorganic & Medicinal Chemistry Letters, Bd. 11, Nr. 9, 2020, S. 1739–1744

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acsmedchemlett.0c00284

Petereit J, Duncan O, Murcha MW, Fenske R, Cincu E, Cahn J, Pruzinska A, Ivanova A, Kollipara L, Wortelkamp S, Sickmann A, Lee J, Lister R, Millar AH, Huang S.

Mitochondrial CLPP2 assists coordination and homeostasis of respiratory complexes

Plant Physiology, Bd. 184, Nr. 184, 2020, S. 148–164

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1104/pp.20.00136

Koelbel H, Roos A, van der Ven PFM, Evangelista T, Nolte K, Johnson K, Töpf A, Wilson M, Kress W, Sickmann A, Straub V, Kollipara L, Weis J, Fürst DO, Schara U.

First Clinical and Myopathological Description of a Myofibrillar Myopathy with Congenital Onset and Homozygous Mutation in FLNC

Human mutation, Bd. 41, Nr. 9, 2020, S. 1600–1614

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/humu.24062

Burhenn S, Kratzer J, Franzke J.

Temporal evolution of tellurium emission lines in a capillary dielectric barrier discharge after hydride generation

Spectrochimica Acta Part B-Atomic Spectroscopy, Bd. 171, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.sab.2020.105936

Drees C, Schütz A, Niu G, Franzke J, Vautz W, Brandt S.

Stepwise optimization of a Flexible Microtube Plasma (FµTP) as an ionization source for Ion Mobility Spectrometry

Analytica Chimica Acta, Bd. 1127, 2020, S. 89–97

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.aca.2020.06.018

Kopczynski D, Hoffmann N, Peng B, Ahrends R.

Goslin - A Grammar of Succinct Lipid Nomenclature

Analytical Chemistry, Bd. 92, Nr. 16, 2020, S. 10957–10960

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.analchem.0c01690

Kasabri V, Arabiyat S, Al-Hiari Y, Zalloum H, Almaliti J, Telfah A, Bustanji YK, Alalawi S.

Fluoroquinolones as a potentially novel class of antidiabesity and antiproliferative compounds: synthesis and docking studies

Canadian Journal of Chemistry, Bd. 98, Nr. 10, 2020, S. 635–645

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1139/cjc-2020-0162

Sunoqrot S, Mahmound NN, Ibrahim LH, Al-Dabash S, Raschke H, Hergenröder R.

Tuning the Surface Chemistry of Melanin-Mimetic Polydopamine Nanoparticles Drastically Enhances Their Accumulation into Excised Human Skin

ACS Biomaterials Science & Engineering, Bd. 6, Nr. 8, 2020, S. 4424–4432

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acsbiomaterials.0c00196

Kahler JP, Vanhoutte R, Verhelst SHL.

Activity-Based Protein Profiling of Serine Proteases in Immune Cells

Archivum immunologiae et therapiae experimentalis, Bd. 68, Nr. 4, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s00005-020-00586-2

Vogel P, Lazarou C, Gazeli O, Brandt S, Franzke J, Moreno-González D.

Study of Controlled Atmosphere Flexible Microtube Plasma Soft Ionization Mass Spectrometry for Detection of Volatile Organic Compounds as Potential Biomarkers in Saliva for Cancer

Analytical Chemistry, Bd. 92, Nr. 14, 2020, S. 9722–9729

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.analchem.0c01063

Khatib-Massalha E, Bhattacharya S, Massalha H, Biram A, Golan K, Kollet O, Kumari A, Avemaria F, Petrovich-Kopitman E, Gur-Cohen S, Itkin T, Brandenburger I, Spiegel A, Shulman Z, Gerhart-Hines Z, Itzkovitz S, Gunzer M, Offermanns S, Alon R, Ariel A, Lapidot T.

Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling.

Nature Communications, Bd. 11, Nr. 1, 2020, S. 3547

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41467-020-17402-2

Bornemann L, Schuster M, Schmitz S, Sobczak C, Bessen C, Merz SF, Jöckel KH, Haverkamp T, Gunzer M, Göthert JR.

Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib

BMC cancer, Bd. 20, Nr. 1, 2020, S. 650

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1186/s12885-020-07130-7

Hinrichs K, Kratz C, Furchner A.

Hyperspectral mid-infrared ellipsometric measurements in the twinkling of an eye

Spectroscopy Asia, Bd. 16, Nr. 2, 2020, S. 8–12

Type: Zeitschriftenbeitrag

DOI: /doi.org/https://www.spectroscopyasia.com/content/volume-16-issue-2-2020

Furchner A, Kratz C, Hinrichs K.

Laser IR ellipsometry for surface analytics - Hyperspectral and microfluidic applications

2020

Reihe: Laser IR ellipsometry for surface analytics

Type: Buchbeitrag

DOI: /doi.org/https://analyticalscience.wiley.com/do/10.1002/was.00080139

Swieringa F, Solari F, Pagel O, Beck F, Huang J, Feijge M, Jurk K, Koerver-Keularts IMLW, Mattheij NJA, Faber J, Pohlenz J, Russo A, Stumpel CTRM, Schrander DE, Zieger B, van der Meijden P, Zahedi RP, Sickmann A, Heemskerk JWM.

Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

Scientific reports, Bd. 10, Nr. 1, 2020, S. 11389

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41598-020-68379-3

Ebersbach P, Münchberg U, Freier E.

SERS Background Imaging – a Versatile Tool Towards More Reliable SERS Analytics

ChemRxiv, 2020

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.26434/chemrxiv.12589013

Jeanclos E, Knobloch G, Hoffmann A, Fedorchenko O, Odersky A, Lamprecht AK, Schindelin H, Gohla A.

Ca2+ functions as a molecular switch that controls the mutually exclusive complex formation of pyridoxal phosphatase with CIB1 or Calmodulin

FEBS Letters, Bd. 594, Nr. 13, 2020, S. 2099–2115

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/1873-3468.13795