Publikationen

Moreno-Gonzalez D, Castilla-Fernandez D, Vogel P, Niu G, Brandt S, Drees C, García-Reyes JF, Molina-Díaz A, Franzke J.

Evaluation of a novel controlled-atmosphere flexible microtube plasma soft ionization source for the determination of BTEX in olive oil by headspace-gas chromatography/mass spectrometry

Analytica Chimica Acta, Bd. 1179, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.aca.2021.338835

Abad C, Minus S, Recknagel S, Jakubowski N, Panne U, Becker-Roß H, Huang MD.

Determination of organic chlorine in water via AlCl derivatization and detection by high-resolution continuum source graphite furnace molecular absorption spectrometry

Analytical Methods, Bd. 13, Nr. 33, 2021, S. 3724–3730

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1039/D1AY00430A

Hathazi D, Cox D, D'Amico A, Tasca G, Charlton R, Carlier RY, Baumann J, Kollipara L, Zahedi RP, Feldmann I, Deleuze JF, Torella A, Cohn R, Robinson E, Ricci F, Jungbluth H, Fattori F, Boland A, O'Connor E, Horvath R, Barresi R, Lochmüller H, Urtizberea A, Jacquemont ML, Nelson I, Swan LE, Bonne G, Roos A.

INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH

Brain, Bd. 144, Nr. 8, 2021, S. 2427–2442

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1093/brain/awab133

Knitsch R, Alwahsh M, Lambert J, Raschke H, Hergenröder R.

In vitro spatio-temporal NMR metabolomics of living 3D cell models

Analytical Chemistry, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.analchem.1c02221

Unterumsberger R, Beckhoff B, Gross A, Stosnach H, Nowak S, Stenzel YP, Kramer M, von Bohlen A.

A round robin test for total reflection X-ray fluorescence analysis using preselected and well characterized samples

Journal of Analytical Atomic Spectrometry, Bd. 36, Nr. 9, 2021, S. 1933–1945

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1039/d1ja00103e

Migdadi LYH, Lambert J, Telfah A, Hergenröder R, Wöhler C.

Automated Metabolic Assignment: Semi-Supervised Learning in Metabolic Analysis Employing Two Dimensional Nuclear Magnetic Resonance (NMR)

Computational and Structural Biotechnology journal, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.csbj.2021.08.048

Rufo N, Korovesis D, Van Eygen S, Derua R, Garg AD, Finotello F, Vara-Perez M, Rozanc J, Dewaele M, de Witte PA, Alexopoulos LG, Janssens S, Sinkkonen L, Sauter T, Verhelst SHL, Agostinis P.

Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1 alpha kinase inhibitor KIRA6 through HSP60 targeting

Cell Death and Differentiation, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41418-021-00853-5

Beck S, Stegner D, Loroch S, Baig AA, Goeb V, Schumbrutzki C, Eilers E, Sickmann A, May F, Nolte MW, Panousis C, Nieswandt B.

Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents

Journal of Thrombosis and Haemostasis : JTH, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1111/jth.15488

Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn LT, Thomalla D, Huelsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP.

MARCKS affects cell motility and response to BTK inhibitors in CLL

Blood, Bd. 138, Nr. 7, 2021, S. 544–556

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1182/blood.2020009165

Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T.

Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy

European heart journal, Bd. ehab430, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1093/eurheartj/ehab430

Hamadneh L, Bahader M, abuarqoub R, Alwahsh M, Alhusban A, Jasim S.

PI3K/AKT and MAPK1 Molecular Changes Preceding Matrix Metallopeptidases Overexpression during Tamoxifen Resistance Development are Correlated to Poor Prognosis in Breast Cancer Patients

BMC Breast Cancer Research, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s12282-021-01277-2

Hamadneh L, Bahader M, abuarqoub R, Alwahsh M, Alhusban A, Hikmat S.

PI3K/AKT and MAPK1 molecular changes preceding matrix metallopeptidases overexpression during tamoxifen-resistance development are correlated to poor prognosis in breast cancer patients

Breast cancer (Tokyo, Japan), 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s12282-021-01277-2

Manke MC, Geue S, Coman C, Peng B, Kollotzek F, Münzer P, Walker B, Huber SM, Rath D, Sickmann A, Stegner D, Duerschmied D, Lang F, Nieswandt B, Gawaz M, Ahrends R, Borst O.

ANXA7 Regulates Platelet Lipid Metabolism and Ca2+ Release in Arterial Thrombosis

Circulation Research, Bd. 129, Nr. 4, 2021, S. 494–507

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1161/CIRCRESAHA.121.319207

Kahler JP, Verhelst SHL.

Phosphinate esters as novel warheads for activity-based probes targeting serine proteases

RSC chemical biology, Bd. 2, Nr. 4, 2021, S. 1285–1290

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1039/d1cb00117e

Fatangare A, Glässner A, Sachs B, Sickmann A.

Future perspectives on in-vitro diagnosis of drug allergy by the lymphocyte transformation test

Journal of immunological methods, Bd. 495, 2021, S. 113072

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.jim.2021.113072

Braun F, Hentschel A, Sickmann A, Marteau T, Hertel S, Foerster F, Prokisch H, Wagner M, Wortmann S, Della Marina A, Koelbel H, Roos A, Schara-Schmidt U.

Muscular and Molecular Pathology Associated with SPATA5 Deficiency in a Child with EHLMRS

International Journal of Molecular Sciences, Bd. 22, Nr. 15, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/ijms22157835

Merk V, Speiser E, Werncke W, Esser N, Kneipp J.

pH-Dependent Flavin Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Ultraviolet Resonance Raman (UVRR) Spectra at Intracellular Concentration

Applied Spectroscopy, Bd. 75, Nr. 8, 2021, S. 994–1002

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1177/00037028211025575

Gazeli O, Lazarou C, Niu G, Anastassiou C, Georghiou GE, Franzke J.

Propagation dynamics of a helium micro-tube plasma

Spectrochimica Acta Part B-Atomic Spectroscopy, Bd. 182, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.sab.2021.106248

Lill JK, Thiebes S, Pohl JM, Bottek J, Subramaniam N, Christ R, Soun C, Gueler F, Zwanziger D, Hoffmann F, von Eggeling F, Bracht T, Sitek B, Hickey MJ, Hofnagel O, Engel DR.

Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga toxin-induced hemolytic uremic syndrome

Kidney international, Bd. 100, Nr. 2, 2021, S. 349–363

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.kint.2021.03.039

Kerp H, Hönes GS, Tolstik E, Hönes-Wendland J, Gassen J, Moeller LC, Lorenz K, Führer D.

Protective Effects of Thyroid Hormone Deprivation on Progression of Maladaptive Cardiac Hypertrophy and Heart Failure

Frontiers in cardiovascular medicine, Bd. 8, 2021, S. 683522

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3389/fcvm.2021.683522

Mohammed Y, Bhowmick P, Michaud SA, Sickmann A, Borchers CH.

Mouse Quantitative Proteomics Knowledgebase

Bioinformatics, Bd. 37, Nr. 13, 2021, S. 1900–1908

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1093/bioinformatics/btab018

Sanna S, Plaickner J, Holtgrewe K, Wettig VM, Speiser E, Chandola S, Esser N.

Spectroscopic Analysis of Rare-Earth Silicide Structures on the Si(111) Surface

Materials, Bd. 14, Nr. 15, 2021, S. 4104

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/ma14154104

Ok K, Filipovic MR, Michel SLJ.

Targeting Zinc Finger Proteins with Exogenous Metals and Molecules

European journal of inorganic chemistry, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/ejic.202100402

Walter C, Marada A, Suhm T, Ernsberger R, Muders V, Kücükköse C, Sánchez-Martín P, Hu Z, Aich A, Loroch S, Solari F, Poveda-Huertes D, Schwierzok A, Pommerening H, Matic S, Brix J, Sickmann A, Kraft C, Dengjel J, Dennerlein S, Brummer T, Vögtle FN, Meisinger C.

Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery

Nature Communications, Bd. 12, Nr. 1, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41467-021-24426-9

Tian C, Ahlmann N, Brandt S, Franzke J, Niu G.

Optical characterization of miniature flexible micro-tube plasma (FμTP) ionization source: A dielectric guided discharge

Spectrochimica Acta Part B-Atomic Spectroscopy, Nr. 181, 2021, S. 106222

Type: Zeitschriftenbeitrag

Korovesis D, Beard HA, Mérillat C, Verhelst SHL.

Probes for Photoaffinity Labelling of Kinases

ChemBioChem, Bd. 22, Nr. 13, 2021, S. 2206–2218

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/cbic.202000874

Farhat J, Pandey I, Alwahsh M.

Transcending toward Advanced 3D-Cell Culture Modalities

Cells, Bd. 10, Nr. 7, 2021, S. 1657

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/cells10071657

Petrovic D, Kouroussis E, Vignane T, Filipovic MR.

The Role of Protein Persulfidation in Brain Aging and Neurodegeneration

Frontiers in aging neuroscience, Bd. 13, 2021, S. 674135

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3389/fnagi.2021.674135

Kienle K, Glaser KM, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, Epple MW, Gunzer M, Baumeister R, Tarrant TK, Germain RN, Irimia D, Kastenmüller W, Lämmermann T.

Neutrophils self-limit swarming to contain bacterial growth in vivo

Science, Bd. 372, Nr. 6548, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1126/science.abe7729

Castilla-Fernandez D, Moreno-Gonzalez D, García-Reyes JF, Ballesteros E, Molina-Díaz A.

Determination of atropine and scopolamine in spinach-based products contaminated with genus Datura by UHPLC-MS/MS

Food Chemistry, Bd. 347, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.foodchem.2021.129020

Huang J, Swieringa F, Solari F, Provenzale I, Grassi L, De Simone I, Baaten C, Cavill R, Sickmann A, Frontini M, Heemskerk JWM.

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

Scientific reports, Bd. 11, Nr. 1, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41598-021-91661-x

Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM.

Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice

Basic Research in Cardiology, Bd. 116, Nr. 1, 2021, S. 40

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s00395-021-00881-9

Cheung HYF, Coman C, Westhoff P, Manke M, Sickmann A, Borst O, Gawaz M, Watson SP, Heemskerk JWM, Ahrends R.

Targeted Phosphoinositides Analysis Using High-Performance Ion Chromatography-Coupled Selected Reaction Monitoring Mass Spectrometry

Journal of Proteome Research, Bd. 20, Nr. 6, 2021, S. 3114–3123

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.jproteome.1c00017

Gucum S, Sakson R, Hoffmann M, Grote V, Becker C, Pakari K, Beedgen L, Thiel C, Rapp E, Ruppert T, Thumberger T, Wittbrodt J.

A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation

Development, Bd. 148, Nr. 11, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1242/dev.199385

Topf A, Pyle A, Griffin H, Schon K, N.N. , N.N. , Sickmann A, Schara-Schmidt U, Hentschel A, Chinnery PF, Koelbel H, Roos A, Horvath R.

Exome reanalysis and proteomic profiling identified TRIP4 as a novel cause of cerebellar hypoplasia and spinal muscular atrophy (PCH1)

European journal of human genetics, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1038/s41431-021-00851-8

Sueiro-Olivares M, Scott J, Gago S, Petrovic D, Kouroussis E, Zivanovic J, Yu Y, Strobel M, Cunha C, Thomson D, Fortune-Grant R, Thusek S, Bowyer P, Beilhack A, Carvalho A, Bignell E, Filipovic MR, Amich J.

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

Plos biology, Bd. 19, Nr. 6, 2021, S. e3001247

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1371/journal.pbio.3001247

Sachs B, Fatangare A, Sickmann A, Glassner A.

Lymphocyte transformation test

Journal of immunological methods, Bd. 493, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.jim.2021.113036

Pfeiffer J, Lorenz K.

Murine models for heart failure: Their creation and applicability to human still require critical and careful considerations

IJC Heart & Vessels, Bd. 34, Nr. 34, 2021, S. 100781

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.ijcha.2021.100781

Cirksena K, Hutte HJ, Shcherbakova A, Thumberger T, Sakson R, Weiss S, Jensen LR, Friedrich A, Todt D, Kuss AW, Ruppert T, Wittbrodt J, Bakker H, Buettner FFR.

The C-Mannosylome of Human Induced Pluripotent Stem Cells Implies a Role for ADAMTS16 C-Mannosylation in Eye Development

Molecular & Cellular Proteomics, Bd. 20, 2021, S. 100092

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.mcpro.2021.100092

Jender M, Höving S, Novo P, Freier E, Janasek D.

Coupling Miniaturized Free-Flow Electrophoresis to Mass Spectrometry via a Multi-Emitter ESI Interface

Analytical Chemistry, Bd. 93, Nr. 19, 2021, S. 7204 – 7209

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acs.analchem.1c00200

Rodríguez-Soacha DA, Fender J, Ramírez YA, Collado JA, Muñoz E, Maitra R, Sotriffer C, Lorenz K, Decker M.

"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar " Cis-On" CB 1 R Antagonist

ACS chemical neuroscience, Bd. 12, Nr. 9, 2021, S. 1632–1647

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1021/acschemneuro.1c00086

Yang J, Mendowicz RJ, Verhelst SHL.

Tagged benzoxazin-4-ones as novel activity-based probes for serine proteases

ChemBioChem, Bd. 22, Nr. 9, 2021, S. 1578–1581

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1002/cbic.202000848

Wagner M, Sadeck MS, Dybkova N, Mason FE, Klehr J, Firneburg R, Cachorro E, Richter K, Klapproth E, Künzel S, Lorenz K, Heijman J, Dobrev D, El-Armouche A, Sossalla S, Kämmerer S.

Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression

International Journal of Molecular Sciences, Bd. 22, Nr. 9, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/ijms22094816

Shevchuk O, Jurak Begonja A, Gambaryan S, Totzeck M, Rassaf T, Huber TB, Greinacher A, Renné T, Sickmann A.

Proteomics

International Journal of Molecular Sciences, Bd. 22, Nr. 9, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.3390/ijms22094776

Singh V, Beer A, Kraus A, Mang F, Zhang X, Xue J, Hagemann N, Hermann DM, Gunzer M.

Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs

Brain behavior and immunity, Bd. 94, 2021, S. 458–462

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.bbi.2021.01.039

Rhoden A, Friedrich FW, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer BM, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F.

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Redox biology, Bd. 41, 2021, S. 101951

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.redox.2021.101951

Stein V, Blank-Landeshammer B, Marker R, Sickmann A, Kueck U.

Targeted Quantification of Phosphorylation Sites Identifies STRIPAK-Dependent Phosphorylation of the Hippo Pathway-Related Kinase SmKIN3

mBio, Bd. 12, Nr. 3, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1128/mBio.00658-21

Drees C, Knieb M, Fechner A, Franzke J, Herweg C, Vautz W.

Detection of illegal treatment of table tennis rackets using gas chromatography coupled to ion mobility spectrometry – A feasibility study

Analytica Chimica Acta, Nr. 1154, 2021

Type: Zeitschriftenbeitrag

Liang Y, Piao C, Beuschel CB, Toppe D, Kollipara L, Bogdanow B, Maglione M, Lützkendorf J, See JCK, Huang S, Conrad TOF, Kintscher U, Madeo F, Liu F, Sickmann A, Sigrist SJ.

eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction

Cell Reports, Bd. 35, Nr. 2, 2021, S. 108941

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1016/j.celrep.2021.108941

Telfah A, Al-Akhras MA, Al-Izzy KA, Ahmad AA, Ababneh R, Ahmad MJA, Tavares CJ, Hergenröder R.

Dielectric Relaxation, XPS and Structural studies of Polyethylene Oxide/IodineComplex Composite Films

Polymer Bulletin, 2021

Type: Zeitschriftenbeitrag

DOI: /doi.org/10.1007/s00289-021-03593-1