Advancing Analytics

We develop and combine technologies into four-dimensional analytical methods for health research. Our goal: With our analytics for precision medicine, we want to contribute to optimising the prevention, diagnosis and therapy of various diseases.

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Research Programmes

In our three programmes, we conduct research on various interdisciplinary projects. In one of our research programmes, for example, we combine analytical procedures and develop multi-method concepts in order to elucidate disease mechanisms and identify potential therapeutic approaches - always with a clear application purpose for the following preclinical research.

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ISAS Compact

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Research programmes

Research Groups

At ISAS, scientists from various disciplines such as biology, chemistry, pharmacology, physics and computer science work hand in hand in twelve research groups.

Career

Tools & Services

Our services include analytical technologies for clinical researchers, collaborative research with other institutions, custom analytics, and standard analytical procedures. We also provide patent-protected innovations for licensing.

Publications

Nature Communications, Vol. 14, No. 1, 2023, P. 3312

Dore R, Watson L, Hollidge S, Krause C, Sentis SC, Oelkrug R, Geißler C, Johann K, Pedaran M, Lyons G, Lopez-Alcantara N, Resch J, Sayk F, Iwen A,…

Resistance to thyroid hormone induced tachycardia in RTHα syndrome

https://doi.org/10.1038/s41467-023-38960-1

Cells, Vol. 2023, No. 12 (13), 2023, P. 1780

Bazgir F, Nau J, Nakhaei-Rad S, Amin E, Wolf MJ, Saucerman JJ, Lorenz K, Ahmadian MR.

The Microenvironment of the Pathogenesis of Cardiac Hypertrophy

http://doi.org/10.3390/cells12131780

Nature Machine Intelligence, 2023

Jia Z, Chen J, Xu X, Kheir J, Hu J, Xiao H, Peng S, Hu X, Chen D, Shi Y.

The importance of resource awareness in artificial intelligence for healthcare

https://doi.org/10.1038/s42256-023-00670-0

Nature Methods, Vol. 20, No. 7, 2023, P. 968-970

Chen J, Viana M, Rafelski S.

When seeing is not believing: application-appropriate validation matters for quantitative bioimage analysis

https://doi.org/10.1038/s41592-023-01881-4

Arthritis & rheumatology (Hoboken, N.J.), Vol. 75, No. 7, 2023, P. 1152-1165

Kaaij MH, van Hamburg JP, van Rooijen CCN, Grüneboom A, Kan YY, Pots D, Schett G, van Ruijven LJ, van Duivenvoorde LM, Huitema LFA, Baeten DLP, Tas…

Contribution of Type H Blood Vessels to Pathologic Osteogenesis and Inflammation in an Experimental Spondyloarthritis Model

https://doi.org/10.1002/art.42449

Journal of the American Society for Mass Spectrometry, Vol. 34, No. 7, 2023, P. 1436-1446

Hormann F, Sommer S, Heiles S.

Formation and Tandem Mass Spectrometry of Doubly Charged Lipid-Metal Ion Complexes

http://doi.org/10.1021/jasms.3c00126

Expert Review of Proteomics, Vol. 20, No. 4-6, 2023, P. 71-86

Wolf M, Schallert K, Knipper L, Sickmann A, Sczyrba A, Benndorf D, Heyer R.

Advances in the clinical use of metaproteomics

https://doi.org/10.1080/14789450.2023.2215440

Thin Solid Films, Vol. 774, No. 774, 2023

Furchner A, Rappich J, Calnan S, Hinrichs K, Peters S.

High-sensitivity IR to UV broadband ellipsometry and transmission characterization of high-purity glasses

https://doi.org/10.1016/j.tsf.2023.139819

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