Advancing Analytics

Between Progress and Footprint: Artificial Intelligence in Healthcare

The potential applications of artificial intelligence in healthcare are constantly increasing. However, with ever better and faster models, the question of sustainability is also coming to the fore. A group of international researchers, including Dr Jianxu Chen from ISAS's AMBIOM group, has been looking into the increased consumption of resources and possible solutions to the impending sustainability problem.

Science Meets Art: Immersion in the Secret World of the Immune System

Diving into the smallest structures of the heart via microscope images? This was possible at the first Dortmund Science Night. "The secret world of the immune system", the immersive 3D experience by storyLab kiU at Fachhochschule Dortmund University of Applied Sciences and Arts and ISAS, gave visitors the chance to experience immune cells up close after a heart attack.

"Book a Scientist": Register Now for a Virtual Chat with Researchers

The format "Book a Scientist" offers those interested in science the opportunity to book individual appointments with researchers within the Leibniz Association. Among them are two ISAS researchers. Their topics are "overzealous" immune cells after a heart attack and animal experiments and their alternatives.

Fascinating Insights: Virtual World in the Classroom

What actually is reality? How do we perceive our environment? And how can augmented reality support researchers in their work? Along with class 3a of the Don Bosco elementary school in Bochum, two ISAS researchers explored these questions.

Protein interaction paralyses a young patient

Two mutations in the genetic material of a boy lead to the rare neuromuscular disease NEDHFBA. Investigations of the young patient's samples by researchers at Essen University Hospital and ISAS shed light on the previously unrecognized mechanisms behind the symptoms: Proteins influence the development of the rare disease.

"We want to improve the fundamental understanding of disease models"

Why is it exciting to decode the lipid signature of individual cells? And which cell type is particularly suitable for allowing this process? Prof Dr Sven Heiles gives the answers in an interview.

"Fatty" signatures: How lipid patterns can be used as a diagnostic tool

Microglial cells, the immune cells of the central nervous system, are known for their different appearances. In order to demonstrate this heterogeneity for the first time at the lipid and thus metabolic level for individual cells, a team of researchers has set itself a special analysis goal: Decoding the unique and "fatty" signatures of individual cells.

Thrombocyte Proteome: Tracking down Life-threatening Events in the Bloodstream

Thrombocytes (blood platelets) can link up at lightning speed and block a vessel as a thrombus. Possible consequences include heart attacks or strokes. Scientists at ISAS are therefore looking for molecular markers for platelet activation. In future, this knowledge could help doctors recognise a thrombosis before it occurs and react accordingly.

 Thyroid hormones: Timers for the heart?

The Collaborative Research Centre "Local Control of Thyroid Hormone Action - LOCOTACT" investigates the local control of the effects of thyroid hormones in organs such as the heart or liver. In order to find new therapeutic approaches for cardiovascular diseases, for example, researchers at ISAS want to know: How does the body control the transport, metabolism and mechanism of action of thyroid hormones in the heart?