Publications

Yang J, Mendowicz RJ, Verhelst SHL.

Tagged benzoxazin-4-ones as novel activity-based probes for serine proteases

ChemBioChem, Vol. 22, Nr. 9, 2021, P. 1578–1581

Type: Journal article

DOI: /doi.org/10.1002/cbic.202000848

Wagner M, Sadeck MS, Dybkova N, Mason FE, Klehr J, Firneburg R, Cachorro E, Richter K, Klapproth E, Künzel S, Lorenz K, Heijman J, Dobrev D, El-Armouche A, Sossalla S, Kämmerer S.

Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression

International Journal of Molecular Sciences, Vol. 22, Nr. 9, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22094816

Shevchuk O, Jurak Begonja A, Gambaryan S, Totzeck M, Rassaf T, Huber TB, Greinacher A, Renné T, Sickmann A.

Proteomics

International Journal of Molecular Sciences, Vol. 22, Nr. 9, 2021

Type: Journal article

DOI: /doi.org/10.3390/ijms22094776

Singh V, Beer A, Kraus A, Mang F, Zhang X, Xue J, Hagemann N, Hermann DM, Gunzer M.

Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs

Brain, Behavior and Immunity, Vol. 94, 2021, P. 458–462

Type: Journal article

DOI: /doi.org/10.1016/j.bbi.2021.01.039

Rhoden A, Friedrich FW, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer BM, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F.

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

Redox biology, Vol. 41, 2021, P. 101951

Type: Journal article

DOI: /doi.org/10.1016/j.redox.2021.101951

Stein V, Blank-Landeshammer B, Marker R, Sickmann A, Kueck U.

Targeted Quantification of Phosphorylation Sites Identifies STRIPAK-Dependent Phosphorylation of the Hippo Pathway-Related Kinase SmKIN3

mBio, Vol. 12, Nr. 3, 2021

Type: Journal article

DOI: /doi.org/10.1128/mBio.00658-21

Jansen P, Mueller H, Lodde GC, Zaremba A, Moeller I, Sucker A, Paschen A, Esser S, Schaller J, Gunzer M, Standl F, Bauer S, Schadendorf D, Mentzel T, Hadaschik E, Griewank KG.

GNA14, GNA11, and GNAQ Mutations Are Frequent in Benign but Not Malignant Cutaneous Vascular Tumors

Frontiers in Genetics, Vol. 12, 2021

Type: Journal article

DOI: /doi.org/10.3389/fgene.2021.663272

Drees C, Knieb M, Fechner A, Franzke J, Herweg C, Vautz W.

Detection of illegal treatment of table tennis rackets using gas chromatography coupled to ion mobility spectrometry – A feasibility study

Analytica Chimica Acta, Nr. 1154, 2021

Type: Journal article

Liang Y, Piao C, Beuschel CB, Toppe D, Kollipara L, Bogdanow B, Maglione M, Lützkendorf J, See JCK, Huang S, Conrad TOF, Kintscher U, Madeo F, Liu F, Sickmann A, Sigrist SJ.

eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction

Cell Reports, Vol. 35, Nr. 2, 2021, P. 108941

Type: Journal article

DOI: /doi.org/10.1016/j.celrep.2021.108941

Telfah A, Al-Akhras MA, Al-Izzy KA, Ahmad AA, Ababneh R, Ahmad MJA, Tavares C, Hergenröder R.

Dielectric relaxation, XPS and structural studies of polyethylene oxide/iodine complex composite films

Polymer Bulletin, 2021

Type: Journal article

DOI: /doi.org/10.1007/s00289-021-03593-1

K Verma S, Kumar Panda P, Kumari P, Patel P, Arunima A, Jha E, Husain S, Prakash R, Hergenröder R, Kumar Mishra Y, Ahuja R, S Verma R, Suar M.

Determining factors for the nano-biocompatibility of cobalt oxide nanoparticles

Green Chemistry, Vol. 23, Nr. 9, 2021, P. 3439–3458

Type: Journal article

DOI: /doi.org/10.1039/D1GC00571E

Drees C, Höving S, Vautz W, Franzke J, Brandt S.

3D-PRINTING OF A COMPLETE MODULAR ION MOBILITY SPECTROMETER

Materials Today, Vol. 44, 2021, P. 58–68

Type: Journal article

DOI: /doi.org/10.1016/j.mattod.2020.10.033

Mahajan A, Hasíková L, Hampel U, Grüneboom A, Shan X, Herrmann I, Garreis F, Bock F, Knopf J, Singh J, Schauer C, Mahajan S, Leppkes M, Paulsen F, Schlötzer-Schrehardt U, Krenn V, Jünemann A, Hohberger B, Schett G, Herrmann M, Muñoz LE.

Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation

The Ocular Surface, Vol. 20, Nr. 20, 2021, P. 1–12

Type: Journal article

DOI: /doi.org/10.1016/j.jtos.2020.12.005

Beard HA, Korovesis D, Chen S, Verhelst SHL.

Cleavable linkers and their application in MS-based target identification

Molecular Omics, Vol. 17, Nr. 2, 2021, P. 197–209

Type: Journal article

DOI: /doi.org/10.1039/d0mo00181c

Andreev D, Liu M, Kachler K, Llerins Perez M, Kirchner P, Kölle J, Gießl A, Rauber S, Song R, Aust O, Grüneboom A, Kleyer A, Cañete JD, Ekici A, Ramming A, Finotto S, Schett G, Bozec A.

Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis

Annals of the rheumatic diseases, Vol. 2021, Nr. 4, 2021, P. 451–468

Type: Journal article

DOI: /doi.org/10.1136/annrheumdis-2020-218902

Henneberg S, Hasenberg A, Maurer A, Neumann F, Bornemann L, Gonzalez-Menendez I, Kraus A, Hasenberg M, Thornton CR, Pichler BJ, Gunzer M, Beziere N.

Antibody-guided in vivo imaging of Aspergillus fumigatus lung infections during antifungal azole treatment

Nature Communications, Vol. 12, Nr. 1, 2021, P. 1707

Type: Journal article

DOI: /doi.org/10.1038/s41467-021-21965-z

Straka T, Schröder C, Roos A, Kollipara L, Sickmann A, Williams MPI, Hafner M, Khan MM, Rudolf R.

Regulatory Function of Sympathetic Innervation on the Endo/Lysosomal Trafficking of Acetylcholine Receptor

Frontiers in Physiology, Vol. 12, 2021, P. 626707

Type: Journal article

DOI: /doi.org/10.3389/fphys.2021.626707

Huang MD, Esser N, Hinrichs K, Tan Q, Rappich J, Nickel N, Dittrich T.

Determination of residual dimethyl sulfoxide by high-resolution continuum source graphite furnace molecular absorption spectrometry

Spectrochimica Acta Part B-Atomic Spectroscopy, Vol. 177, 2021

Type: Journal article

DOI: /doi.org/10.1016/j.sab.2020.106050

Grande V, Hathazi D, O'Connor E, Marteau T, Schara-Schmidt U, Hentschel A, Gourdon G, Nikolenko N, Lochmüller H, Roos A.

Dysregulation of GSK3β-Target Proteins in Skin Fibroblasts of Myotonic Dystrophy Type 1 (DM1) Patients

Journal of Neuromuscular Diseases, Vol. 2021, Nr. vol. 8, no. 4, 2021, P. 603–619

Type: Journal article

DOI: /doi.org/10.3233/JND-200558

Al-Bataineh QM, Ahmad AA, Alsaad AM, Aljarrah I, Qattan IA, Telfah A.

Effect of Iodine Filler on Photoisomerization Kinetics of Photo-Switchable Thin Films Based on PEO-BDK-MR

Polymers, Vol. 13, Nr. 5, 2021, P. 841

Type: Journal article

DOI: /doi.org/10.3390/polym13050841

Rolfes L, Riek-Burchardt M, Pawlitzki M, Minnerup J, Bock S, Schmidt M, Meuth SG, Gunzer M, Neumann J.

Neutrophil granulocytes promote flow stagnation due to dynamic capillary stalls following experimental stroke

Brain, Behavior and Immunity, Vol. 93, Nr. 93, 2021, P. 322–330

Type: Journal article

DOI: /doi.org/10.1016/j.bbi.2021.01.011

Winneberger J, Schoels S, Lessmann K, Randez-Garbayo J, Bauer AT, Mohamud Yusuf A, Hermann DM, Gunzer M, Schneider SW, Fiehler J, Gerloff C, Gelderblom M, Ludewig P, Magnus T.

Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke

Brain, Behavior and Immunity, Vol. 93, 2021, P. 277–287

Type: Journal article

DOI: /doi.org/10.1016/j.bbi.2020.12.026

Klopfenstein N, Brandt SL, Castellanos S, Gunzer M, Blackman A, Serezani CH.

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

PLoS Pathogens, Vol. 17, Nr. 3, 2021, P. e1009387

Type: Journal article

DOI: /doi.org/10.1371/journal.ppat.1009387

Dümig M, Binder J, Gaculenko A, Daul F, Winandy L, Hasenberg M, Gunzer M, Fischer R, Künzler M, Krappmann S.

The infectious propagules of Aspergillus fumigatus are coated with antimicrobial peptides

Cellular Microbiology, Vol. 23, Nr. 3, 2021, P. e13301

Type: Journal article

DOI: /doi.org/10.1111/cmi.13301

Pech S, Rehberg M, Janke R, Benndorf D, Genzel Y, Muth T, Sickmann A, Rapp E, Reichl U.

Tracking changes in adaptation to suspension growth for MDCK cells

Applied Microbiology and Biotechnology, Vol. 105, Nr. 5, 2021, P. 1861–1874

Type: Journal article

DOI: /doi.org/10.1007/s00253-021-11150-z

Niu G, Knodel A, Burhenn S, Brandt S, Franzke J.

Review: Miniature dielectric barrier discharge (DBD) in analytical atomic spectrometry

Analytica Chimica Acta, Vol. 2020, 2021, P. 221–239

Type: Journal article

Barniol-Xicota M, Verhelst SHL.

Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes

Communications Biology, Vol. 4, Nr. 1, 2021

Type: Journal article

DOI: /doi.org/10.1038/s42003-021-01711-3

Hentschel A, Czech AA, Münchberg U, Freier E, Schara-Schmidt U, Sickmann A, Reimann J, Roos A.

Protein Signature of Human Skin Fibroblasts Allows the Study of the Molecular Etiology of Rare Neurological Diseases

Orphanet journal of rare diseases, Vol. 16, 2021

Type: Journal article

DOI: /doi.org/10.21203/rs.3.rs-48014/v1

Klute D, Brandt S, Franzke J.

Spatiotemporal characterization of different dielectric barrier discharges designed for soft ionization

Spectrochimica Acta Part B-Atomic Spectroscopy, Nr. 176, 2021, P. 106037

Type: Journal article

DOI: /doi.org/10.1016/j.sab.2020.106037

Mülling K, Fischer AJ, Siakaeva E, Richter M, Bordbari S, Spyra I, Köster C, Hermann DM, Gunzer M, Felderhoff-Müser U, Bendix I, Jablonska J, Herz J.

Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia-ischemia

Brain, Behavior and Immunity, Vol. 92, 2021, P. 232–242

Type: Journal article

DOI: /doi.org/10.1016/j.bbi.2020.12.012

Andes FT, Adam S, Hahn M, Aust O, Frey S, Grüneboom A, Nitschke L, Schett G, Steffen U.

The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption

Bone, Vol. 143, 2021, P. 115665

Type: Journal article

DOI: /doi.org/10.1016/j.bone.2020.115665

Rassaf T, Totzeck M, Mahabadi AA, Hendgen-Cotta UB, Korste S, Settelmeier S, Luedike P, Dittmer U, Herbstreit F, Brenner T, Klingel K, Hasenberg M, Walkenfort B, Gunzer M, Schlosser T, Weymann A, Kamler M, Schmack B, Ruhparwar A.

Ventricular assist device for a coronavirus disease 2019-affected heart

ESC heart failure, Vol. 8, Nr. 1, 2021, P. 162–166

Type: Journal article

DOI: /doi.org/10.1002/ehf2.13120

Giovinazzo D, Bursac B, Sbodio J, Nalluru S, Vignane T, Snowman AM, Albacarys LM, Sedlak TW, Torregrossa R, Whiteman M, Filipovic MR, Snyder SH, Paul BD.

Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Nr. 4, 2021

Type: Journal article

DOI: /doi.org/10.1073/pnas.2017225118

Gungor S, Oktay Y, Hiz S, Aranguren-Ibánez �, Kalafatcîlar I, Yaramis A, Karaca E, Yis U, Sonmezler E, Ekinci B, Aslan M, Yilmaz E, Özgör B, Balaraju S, Szabo N, Laurie S, Beltran S, MacArthur DG, Hathazi D, Töpf A, Roos A, Lochmüller H, Vernos I, Horvath R.

Autosomal recessive variants inTUBGCP2alter theg-tubulin ring complex leading toneurodevelopmental disease

iScience, Vol. 24, Nr. 1, 2021, P. 101948

Type: Journal article

DOI: /doi.org/10.1016/j.isci.2020.101948

Van Kersavond T, Konopatzki R, van de Plassche MAT, Yang J, Verhelst SHL.

Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors

RSC Advances, Vol. 11, Nr. 7, 2021, P. 4196–4199

Type: Journal article

DOI: /doi.org/10.1039/d0ra10614c

Hermann DM, Gunzer M.

Modulating Microglial Cells for Promoting Brain Recovery and Repair

Frontiers in Cellular Neuroscience, Vol. 14, 2021, P. 627987

Type: Journal article

DOI: /doi.org/10.3389/fncel.2020.627987

Mohamud Yusuf A, Hagemann N, Schulten S, Rausch O, Wagner K, Hussner T, Qi Y, Totzeck M, Kleinschnitz C, Squire A, Gunzer M, Hermann DM.

Light Sheet Microscopy Using FITC-Albumin Followed by Immunohistochemistry of the Same Rehydrated Brains Reveals Ischemic Brain Injury and Early Microvascular Remodeling

Frontiers in Cellular Neuroscience, Vol. 14, 2021, P. 625513

Type: Journal article

DOI: /doi.org/10.3389/fncel.2020.625513

Dalal PJ, Sullivan DP, Weber EW, Sacks DB, Gunzer M, Grumbach IM, Heller Brown J, Muller WA.

Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration

Journal of Experimental Medicine, Vol. 218, Nr. 1, 2021

Type: Journal article

DOI: /doi.org/10.1084/jem.20192378

Schneidereit D, Bröllochs A, Ritter P, Kreiß L, Mokhtari Z, Beilhack A, Krönke G, Ackermann JA, Faas M, Grüneboom A, Schürmann S, Friedrich O.

An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle

Theranostics, Vol. 11, Nr. 6, 2021, P. 2876–2891

Type: Journal article

DOI: /doi.org/10.7150/thno.51558

Hamouda NN, Van den Haute C, Vanhoutte R, Sannerud R, Azfar M, Mayer R, Cortés Calabuig �, Swinnen JV, Agostinis P, Baekelandt V, Annaert W, Impens F, Verhelst SHL, Eggermont J, Martin S, Vangheluwe P.

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

Journal of Biological Chemistry, Vol. 296, 2021, P. 100182

Type: Journal article

DOI: /doi.org/10.1074/jbc.RA120.013908

Al-Bataineh QM, Ahmad AA, Mohammad Alsaad A, Telfah A.

Optical characterizations of PMMA/metal oxide nanoparticles thin films: bandgap engineering using a novel derived model

Heliyon, Vol. 7, Nr. 1, 2021, P. e05952

Type: Journal article

DOI: /doi.org/10.1016/j.heliyon.2021.e05952

Drepper F, Biernat J, Kaniyappan S, Meyer HE, Mandelkow EM, Warscheid B, Mandelkow E.

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

Journal of Biological Chemistry, Vol. 295, Nr. 52, 2020, P. 18213–18225

Type: Journal article

DOI: /doi.org/10.1074/jbc.RA120.015882

Verhelst SHL, Bonger KM, Willems LI.

Bioorthogonal Reactions in Activity-Based Protein Profiling

Molecules, Vol. 25, Nr. 24, 2020

Type: Journal article

DOI: /doi.org/10.3390/molecules25245994

Jender M, Höving S, Novo P, Freier E, Janasek D.

Coupling miniaturized free-flow electrophoresis to mass spectrometry via a multi-emitter ESI interface

ChemRxiv, 2020

Type: Journal article

DOI: /doi.org/10.26434/chemrxiv.13386758

Korovesis D, Rufo N, Derua R, Agostinis P, Verhelst SHL.

Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor

ACS Chemical Biology, Vol. 15, Nr. 12, 2020, P. 3106–3111

Type: Journal article

DOI: /doi.org/10.1021/acschembio.0c00802

Danne-Rasche N, Rubenzucker S, Ahrends R.

Uncovering the complexity of the yeast lipidome by means of nLC/NSI-MS/MS

Analytica Chimica Acta, Vol. 1140, 2020, P. 199–209

Type: Journal article

DOI: /doi.org/10.1016/j.aca.2020.10.012

van Geffen JP, Swieringa F, van Kuijk K, Tullemans BME, Solari F, Peng B, Clemetson KJ, Farndale RW, Dubois LJ, Sickmann A, Zahedi RP, Ahrends R, Biessen EAL, Sluimer JC, Heemskerk JWM, Kuijpers MJE.

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

Scientific reports, Vol. 10, Nr. 1, 2020

Type: Journal article

DOI: /doi.org/10.1038/s41598-020-78522-9

Gunzer M, Thornton CR, Beziere N.

Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis

Journal of Fungi, Vol. 6, Nr. 4, 2020, P. 1–15

Type: Journal article

DOI: /doi.org/10.3390/jof6040338

Hathazi D, Griffin H, Jennings MJ, Giunta M, Powell C, Pearce SF, Munro B, Wei W, Boczonadi V, Poulton J, Pyle A, Calabrese C, Gomez-Duran A, Schara U, Pitceathly RDS, Hanna MG, Joost K, Cotta A, Paim JF, Navarro MM, Duff J, Mattman A, Chapman K, Servidei S, Della Marina A, Uusimaa J, Roos A, Mootha V, Hirano M, Tulinius M, Giri M, Hoffmann EP, Lochmüller H, DiMauro S, Minczuk M, Chinnery PF, Mueller JS, Horvath R.

Metabolic shift underlies recovery in reversible infantile respiratory chain deficiency

The EMBO journal, Vol. 39, Nr. 23, 2020

Type: Journal article

DOI: /doi.org/10.15252/embj.2020105364

van de Plassche MAT, Barniol-Xicota M, Verhelst SHL.

Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2

ChemBioChem, Vol. 21, Nr. 23, 2020, P. 3383–3388

Type: Journal article

DOI: /doi.org/10.1002/cbic.202000371