New findings about the composition, structure and dynamics of new materials and biological systems can only be obtained by developing innovative analytical (measuring) processes. The knowledge gained in this manner is crucial for deepening our understanding of the causes of disease on a molecular level, paves the way to more precise, personalized medical treatments, and is a key to the characterization and development of new, treatment-improving materials; it calls for and is subject to a constant process of optimization.
The scientific work at ISAS concerns the development of new methods on all levels – from basic research through to the production of prototypes. The following pages will provide you with detailed information about our research topics and projects.
Research programmes
Disease Mechanisms and Targets
The projects in the Disease Mechanisms and Targets programme focus on a central aspect of health research: the investigation of molecular mechanisms that are involved in pathogenesis.
The projects in the Biomarkers programme focus on the identification and validation of biomarkers as well as on the improved detection of such molecules in a complex biological matrix.
ISAS uses its long-standing experience in optical spectroscopy to develop its methods towards imaging applications for health research. In the Imaging programme, methods such as Raman spectroscopy, high-resolution fluorescence, or CARS microscopy are combined to develop novel analytical platforms.
The projects in this programme focus on non-destructive and non-invasive analytical methods for minute samples of biomolecules on solid-liquid surfaces. Such biohybrid interfaces are especially suited for sensors or for studying biomolecular interactions, cell templates, and biomolecule binding to surfaces.
The objective of the Strategy Fund “Competition” is to promote scientific ideas that particularly support the strategic aims of ISAS. For this internal competition, the institute has established the funding lines “Integrative Research” and “Early Independence”, which are advertised alternately.
Optical characterization of miniature flexible micro-tube plasma (FμTP) ionization source: A dielectric guided discharge
Spectrochimica Acta Part B-Atomic Spectroscopy, Nr. 181, , P. 106222
Type: Journal article
Gregorius J,
Wang C,
Stambouli O,
Hussner T,
Qi Y,
Tertel T,
Börger V,
Yusuf AM,
Hagemann N,
Yin D,
Dittrich R,
Mouloud Y,
Mairinger FD,
Magraoui FE,
Popa-Wagner A,
Kleinschnitz C,
Doeppner TR,
Gunzer M,
Meyer HE,
Giebel B,
Hermann DM.
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice
Basic Research in Cardiology, Vol. 116, Nr. 1, , P. 40
