Innovative analytics
for health research

New findings about the composition, structure and dynamics of new materials and biological systems can only be obtained by developing innovative analytical (measuring) processes. The knowledge gained in this manner is crucial for deepening our understanding of the causes of disease on a molecular level, paves the way to more precise, personalized medical treatments, and is a key to the characterization and development of new, treatment-improving materials; it calls for and is subject to a constant process of optimization.

The scientific work at ISAS concerns the development of new methods on all levels – from basic research through to the production of prototypes. The following pages will provide you with detailed information about our research topics and projects.

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Research programmes

Disease Mechanisms and Targets

Disease Mechanisms and Targets

The projects in the Disease Mechanisms and Targets programme focus on a central aspect of health research: the investigation of molecular mechanisms that are involved in pathogenesis.

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Biomarkers

Biomarkers

The projects in the Biomarkers programme focus on the identification and validation of biomarkers as well as on the improved detection of such molecules in a complex biological matrix.

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Imaging

Imaging

ISAS uses its long-standing experience in optical spectroscopy to develop its methods towards imaging applications for health research. In the Imaging programme, methods such as Raman spectroscopy, high-resolution fluorescence, or CARS microscopy are combined to develop novel analytical platforms.

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Biointerfaces

Biointerfaces

The projects in this programme focus on non-destructive and non-invasive analytical methods for minute samples of biomolecules on solid-liquid surfaces. Such biohybrid interfaces are especially suited for sensors or for studying biomolecular interactions, cell templates, and biomolecule binding to surfaces.

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ISAS Strategy Fund

ISAS Strategy Fund

The objective of the Strategy Fund “Competition” is to promote scientific ideas that particularly support the strategic aims of ISAS. For this internal competition, the institute has established the funding lines “Integrative Research” and “Early Independence”, which are advertised alternately.

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Recent publications

SERS Background Imaging – a Versatile Tool Towards More Reliable SERS Analytics

ChemRxiv,
Type: Journal article
DOI: /doi.org/10.26434/chemrxiv.12589013

Goslin - A Grammar of Succinct Lipid Nomenclature

Analytical Chemistry,
Type: Journal article
DOI: /doi.org/10.1021/acs.analchem.0c01690

Sensing and structure analysis by in situ IR spectroscopy: From mL flow cells to microfluidic applications

Journal of Physics - Condensed Matter,
Type: Journal article
DOI: /doi.org/https://iopscience.iop.org/article/10.1088/1361-648X/ab8523

Coactosin-like 1 integrates signaling critical for shear-dependent thrombus formation in mouse platelets

Haematologica, Vol. 105, Nr. 6, , P. 1667–1676
Type: Journal article
DOI: /doi.org/10.3324/haematol.2019.225516

Surface Plasmon Resonance (SPR)-Based Biosensors as Instruments with High Versatility and Sensitivity

Sensors, Vol. 20, Nr. 11,
Type: Journal article
DOI: /doi.org/10.3390/s20113010

Identification of novel unspecific peroxygenase chimeras and unusual YfeX axial heme ligand by a versatile high-throughput GC-MS approach

ChemCatChem, Vol. n/a, Nr. n/a,
Type: Journal article
DOI: /doi.org/10.1002/cctc.202000618

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