Miniaturisation

The Miniaturisation work group specialises in developing and characterising miniaturised plasmas for analytical chemistry; one of the objectives of its work is to optimise the work steps involved in mass spectrometry. Reducing the plasmas to a miniature scale lowers the volume of samples required and thus cuts costs and saves resources. In addition, the group works on combining different ionisation processes to enable even mixtures of molecules to be investigated in the simplest way possible.

The group specialises in two ionisation processes: dielectric barrier electrospray ionisation (DB-ESI) and the plasma jet. The aim of the research is to precisely characterise these discharges and to optimise them to the extent that they can be deployed synchronously in mass spectrometry. Both methods enable a soft ionisation which does not fragment the analytes. They can thus also be deployed to analyse very large molecules.

Current Publications

Use of dielectric barrier discharge ionization to minimize matrix effects and expand coverage in pesticide residue analysis by liquid chromatography-mass spectrometry

Analytica Chimica Acta, Vol. 1020, , P. 76–85
Type: Journal article

Mechanistic Understanding Leads to Increased Ionization Efficiency and Selectivity in Dielectric Barrier Discharge Ionization Mass Spectrometry

A Case Study with Perfluorinated Compounds
Analytical Chemistry, Vol. 90, Nr. 4, , P. 2725–2731
Type: Journal article

Soft argon-propane dielectric barrier discharge ionization

Analytical Chemistry,
Type: Journal article

Systematic Comparison between Half and Full Dielectric Barrier Discharges Based on the Low Temperature Plasma Probe (LTP) and Dielectric Barrier Discharge for Soft Ionization (DBDI) Configurations

Analytical Chemistry, Vol. 89, Nr. 17, , P. 9368–9374
Type: Journal article

Determination of Peroxide Explosive TATP and Related Compounds by Dielectric Barrier Discharge Ionization-Mass Spectrometry (DBDI-MS)

Analytical Chemistry, Vol. 89, Nr. 7, , P. 4210–4215
Type: Journal article

Dielectric barrier discharges applied for soft ionization and their mechanism

Analytica Chimica Acta, Vol. 951, , P. 16–31
Type: Journal article