Innovative analytics
for health research

New findings about the composition, structure and dynamics of new materials and biological systems can only be obtained by developing innovative analytical (measuring) processes. The knowledge gained in this manner is crucial for deepening our understanding of the causes of disease on a molecular level, paves the way to more precise, personalized medical treatments, and is a key to the characterization and development of new, treatment-improving materials; it calls for and is subject to a constant process of optimization.

The scientific work at ISAS concerns the development of new methods on all levels – from basic research through to the production of prototypes. The following pages will provide you with detailed information about our research topics and projects.

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Research programmes

Disease Mechanisms and Targets

Disease Mechanisms and Targets

The projects in the Disease Mechanisms and Targets programme focus on a central aspect of health research: the investigation of molecular mechanisms that are involved in pathogenesis.

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Biomarkers

Biomarkers

The projects in the Biomarkers programme focus on the identification and validation of biomarkers as well as on the improved detection of such molecules in a complex biological matrix.

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Biointerfaces

Biointerfaces

The projects in this programme focus on non-destructive and non-invasive analytical methods for minute samples of biomolecules on solid-liquid surfaces. Such biohybrid interfaces are especially suited for sensors or for studying biomolecular interactions, cell templates, and biomolecule binding to surfaces.

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Imaging

Imaging

ISAS uses its long-standing experience in optical spectroscopy to develop its methods towards imaging applications for health research. In the Imaging programme, methods such as Raman spectroscopy, high-resolution fluorescence, or CARS microscopy are combined to develop novel analytical platforms.

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ISAS Strategy Fund

ISAS Strategy Fund

The objective of the Strategy Fund “Competition” is to promote scientific ideas that particularly support the strategic aims of ISAS. For this internal competition, the institute has established the funding lines “Integrative Research” and “Early Independence”, which are advertised alternately.

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Recent publications

Hyphenation of a MEMS based pre-concentrator and GC-IMS

Talanta, Vol. 191, , P. 141–148
Type: Journal article
DOI: /doi.org/10.1016/j.talanta.2018.07.057

Characterisation of self-assembled monolayers for Cu-Cu bonding technology Microelectronic Engineering

Microelectronic Engineering, Vol. 202, Nr. 19-24,
Type: Journal article

Direct-acting antivirals-based therapy decreases hepatic fibrosis serum biomarker microfibrillar-associated protein 4 in hepatitis C patients

Clinical and Molecular Hepatology,
Type: Journal article
DOI: /doi.org/10.3350/cmh.2018.0029

Chemical fingerprinting of single glandular trichomes of Cannabis sativa by Coherent anti-Stokes Raman scattering (CARS) microscopy

BMC Plant Biology, Vol. 18, Nr. 1, , P. 275
Type: Journal article
DOI: /doi.org/10.1186/s12870-018-1481-4

Real-time Triggered RAdial Single-Shot Inversion recovery for arrhythmia-insensitive myocardial T1 mapping: motion phantom validation and in vivo comparison.

Magnetic Resonance in Medicine,
Type: Journal article
DOI: /doi.org/doi:10.1002/mrm.27526

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

Cardiology Research and Practice,
Type: Journal article
DOI: /doi.org/10.1155/2018/3713897

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