Miniaturisation

The Miniaturisation work group specialises in developing and characterising miniaturised plasmas for analytical chemistry; one of the objectives of its work is to optimise the work steps involved in mass spectrometry. Reducing the plasmas to a miniature scale lowers the volume of samples required and thus cuts costs and saves resources. In addition, the group works on combining different ionisation processes to enable even mixtures of molecules to be investigated in the simplest way possible.

The group specialises in two ionisation processes: dielectric barrier electrospray ionisation (DB-ESI) and the plasma jet. The aim of the research is to precisely characterise these discharges and to optimise them to the extent that they can be deployed synchronously in mass spectrometry. Both methods enable a soft ionisation which does not fragment the analytes. They can thus also be deployed to analyse very large molecules.

Current Publications

Ionization of semi-fluorinated n-alkanes in controlled atmosphere using flexible micro-tube plasma (FμTP) ionization source with square- and sine-wave voltage

Talanta, Vol. 249, , P. 123662
Type: Journal article

Liquid chromatography-dielectric barrier discharge ionization mass spectrometry for the analysis of neutral lipids of archaeological interest

Journal of Separation Science, Vol. 45, Nr. 16, , P. 3105–3114
Type: Journal article

Blood Culture Headspace Gas Analysis Enables Early Detection of Escherichia coli Bacteremia in an Animal Model of Sepsis

Antibiotics, Vol. 11, Nr. 8, , P. 992
Type: Journal article

Photoisomerization kinetics of a novel photoswitchable film based on methyl red doped with sodium hexachloroplatinate hosted in polyethylene oxide

Journal of Applied Polymer Science, Vol. 139, Nr. 25,
Type: Journal article

Coupling paper spray ionization with the flexible microtube plasma for the determination of low polar biomarkers in mass spectrometry

Analytica Chimica Acta, Nr. 1201, , P. 339619
Type: Journal article

Pulsed Blue Laser Diode Thermal Desorption Microplasma Imaging Mass Spectrometry

Journal of the American Society for Mass Spectrometry, Vol. 33, Nr. 1, , P. 45–53
Type: Journal article