Bioanalytics

Our work in the Bioanalytics department involves trying to understand the highly complex signalling and metabolic pathways in cells and cell layers in the human body at different levels, from lipids through to intercellular communication processes. Our long-term objective is to improve the health of the general public. To this end, we develop techniques to measure molecule diffusion with spatial and temporal resolution. We hope that these measurement techniques and the results of analyses can be used to help diagnose a variety of illnesses more easily – such as cardiovascular diseases - and perhaps even to develop new therapies. 

In order to explain the multitude of single processes in as much detail and as reliably as possible, we work on living cells and with microchips on which the transport and signalling paths of human cells are simulated.

Current Publications

Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy

Brain pathology, Vol. 32, Nr. 6, , P. e13084
Type: Journal article

Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles

Basic Research in Cardiology, Vol. 117, Nr. 1,
Type: Journal article

The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

Archives of Toxicology, Vol. 96, Nr. 8, , P. 2341–2360
Type: Journal article

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naive Human BMSCs

Cells, Vol. 11, Nr. 16,
Type: Journal article

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naive Human BMSCs

Cells, Vol. 11, Nr. 16,
Type: Journal article

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear

International Journal of Molecular Sciences, Vol. 23, Nr. 15, , P. 8688
Type: Journal article