Bioanalytics

Our work in the Bioanalytics department involves trying to understand the highly complex signalling and metabolic pathways in cells and cell layers in the human body at different levels, from lipids through to intercellular communication processes. Our long-term objective is to improve the health of the general public. To this end, we develop techniques to measure molecule diffusion with spatial and temporal resolution. We hope that these measurement techniques and the results of analyses can be used to help diagnose a variety of illnesses more easily – such as cardiovascular diseases - and perhaps even to develop new therapies. 

In order to explain the multitude of single processes in as much detail and as reliably as possible, we work on living cells and with microchips on which the transport and signalling paths of human cells are simulated.

Current Publications

Short Peptides with Uncleavable Peptide Bond Mimetics as Photoactivatable Caspase-3 Inhibitors

Molecules, Vol. 24, Nr. 1,
Type: Journal article

Activation of E2F-dependent transcription by the mouse cytomegalovirus M117 protein affects the viral host range

PLoS Pathogens, Vol. 14, Nr. 12,
Type: Journal article

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

Cell Metabolism, Vol. 28, Nr. 6, , P. 866–880
Type: Journal article

Advanced tools for the analysis of protein phosphorylation in yeast mitochondria

Analytical Biochemistry, Vol. 554, , P. 23–27
Type: Journal article

Analysis of new growth promoting black market products

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, Vol. 41, , P. 1–6
Type: Journal article

Detecting post-translational modification signatures as potential biomarkers in clinical mass spectrometry

Expert Review of Proteomics, Vol. 15, Nr. 6, , P. 515–535
Type: Journal article