Our work in the Bioanalytics department involves trying to understand the highly complex signalling and metabolic pathways in cells and cell layers in the human body at different levels, from lipids through to intercellular communication processes. Our long-term objective is to improve the health of the general public. To this end, we develop techniques to measure molecule diffusion with spatial and temporal resolution. We hope that these measurement techniques and the results of analyses can be used to help diagnose a variety of illnesses more easily – such as cardiovascular diseases - and perhaps even to develop new therapies. 

In order to explain the multitude of single processes in as much detail and as reliably as possible, we work on living cells and with microchips on which the transport and signalling paths of human cells are simulated.

Current Publications

A Homozygous PPP1R21 Splice Variant Associated with Severe Developmental Delay, Absence of Speech, and Muscle Weakness Leads to Activated Proteasome Function

Molecular Neurobiology,
Type: Journal article

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-kappa B to the nucleus

The EMBO journal, Vol. 41, Nr. 24, , P. e112006
Type: Journal article

Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro

BMC biology, Vol. 20, Nr. 1, , P. 264
Type: Journal article

Proteome-Based Clustering Approaches Reveal Phylogenetic Insights into Amphistegina

Journal of earth science, Vol. 33, Nr. 6, , P. 1469–1479
Type: Journal article

Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry

Platelets, Vol. 33, Nr. 8, , P. 1293–1300
Type: Journal article

Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy

Brain pathology, Vol. 32, Nr. 6, , P. e13084
Type: Journal article